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Nodal is a short-range morphogen with activity that spreads through a relay mechanism in human gastruloids
Morphogens are signaling molecules that convey positional information and dictate cell fates during development. Although ectopic expression in model organisms suggests that morphogen gradients form through diffusion, little is known about how morphogen gradients are created and interpreted during m...
Autores principales: | Liu, Lizhong, Nemashkalo, Anastasiia, Rezende, Luisa, Jung, Ji Yoon, Chhabra, Sapna, Guerra, M. Cecilia, Heemskerk, Idse, Warmflash, Aryeh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789905/ https://www.ncbi.nlm.nih.gov/pubmed/35079017 http://dx.doi.org/10.1038/s41467-022-28149-3 |
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