Cargando…
PIP(2) determines length and stability of primary cilia by balancing membrane turnovers
Primary cilia are sensory organelles on many postmitotic cells. The ciliary membrane is continuous with the plasma membrane but differs in its phospholipid composition with phosphatidylinositol 4,5-bisposphate (PIP(2)) being much reduced toward the ciliary tip. In order to determine the functional s...
Autores principales: | Stilling, Simon, Kalliakoudas, Theodoros, Benninghoven-Frey, Hannah, Inoue, Takanari, Falkenburger, Björn H |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789910/ https://www.ncbi.nlm.nih.gov/pubmed/35079141 http://dx.doi.org/10.1038/s42003-022-03028-1 |
Ejemplares similares
-
Adaptive changes in striatal projection neurons explain the long duration response and the emergence of dyskinesias in patients with Parkinson’s disease
por: Falkenburger, Björn, et al.
Publicado: (2022) -
Balancing the length of the distal tip by septins is key for stability and signalling function of primary cilia
por: Kanamaru, Taishi, et al.
Publicado: (2021) -
Kinetics of PIP(2) metabolism and KCNQ2/3 channel regulation studied with a voltage-sensitive phosphatase in living cells
por: Falkenburger, Björn H., et al.
Publicado: (2010) -
Phosphatidylinositol 5 Phosphate 4-Kinase Regulates Plasma-Membrane
PIP(3) Turnover and Insulin Signaling
por: Sharma, Sanjeev, et al.
Publicado: (2019) -
Striking a balance: PIP(2) and PIP(3) signaling in neuronal health and disease
por: Tariq, Kamran, et al.
Publicado: (2021)