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A Comprehensive Review on Novel Liposomal Methodologies, Commercial Formulations, Clinical Trials and Patents
Liposomes are well-recognized and essential nano-sized drug delivery systems. Liposomes are phospholipid vesicles comprised of cell membrane components and have been employed as artificial cell models to mimic structure and functions of cells and are of immense use in various biological analyses. Li...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790012/ https://www.ncbi.nlm.nih.gov/pubmed/35096502 http://dx.doi.org/10.1007/s12668-022-00941-x |
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author | Andra, Veera Venkata Satya Naga Lakshmi Pammi, S. V. N. Bhatraju, Lakshmi Venkata Krishna Priya Ruddaraju, Lakshmi Kalyani |
author_facet | Andra, Veera Venkata Satya Naga Lakshmi Pammi, S. V. N. Bhatraju, Lakshmi Venkata Krishna Priya Ruddaraju, Lakshmi Kalyani |
author_sort | Andra, Veera Venkata Satya Naga Lakshmi |
collection | PubMed |
description | Liposomes are well-recognized and essential nano-sized drug delivery systems. Liposomes are phospholipid vesicles comprised of cell membrane components and have been employed as artificial cell models to mimic structure and functions of cells and are of immense use in various biological analyses. Liposomes acquire great advantages and provide wide range of applications as useful drug carriers in pre-clinical and clinical trials. This review summarizes exclusively on scalable techniques for liposome preparation and focuses on the strengths and limitations with respect to industrial applicability. Also, this review discusses the updated recent advancements in biomedical applications with a mention of key highlights of commercially available formulations, clinical trials and patents in recent past. Furthermore, this review also provides brief information of the classification, composition and characterization of liposomes. |
format | Online Article Text |
id | pubmed-8790012 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-87900122022-01-26 A Comprehensive Review on Novel Liposomal Methodologies, Commercial Formulations, Clinical Trials and Patents Andra, Veera Venkata Satya Naga Lakshmi Pammi, S. V. N. Bhatraju, Lakshmi Venkata Krishna Priya Ruddaraju, Lakshmi Kalyani Bionanoscience Article Liposomes are well-recognized and essential nano-sized drug delivery systems. Liposomes are phospholipid vesicles comprised of cell membrane components and have been employed as artificial cell models to mimic structure and functions of cells and are of immense use in various biological analyses. Liposomes acquire great advantages and provide wide range of applications as useful drug carriers in pre-clinical and clinical trials. This review summarizes exclusively on scalable techniques for liposome preparation and focuses on the strengths and limitations with respect to industrial applicability. Also, this review discusses the updated recent advancements in biomedical applications with a mention of key highlights of commercially available formulations, clinical trials and patents in recent past. Furthermore, this review also provides brief information of the classification, composition and characterization of liposomes. Springer US 2022-01-26 2022 /pmc/articles/PMC8790012/ /pubmed/35096502 http://dx.doi.org/10.1007/s12668-022-00941-x Text en © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2022 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Article Andra, Veera Venkata Satya Naga Lakshmi Pammi, S. V. N. Bhatraju, Lakshmi Venkata Krishna Priya Ruddaraju, Lakshmi Kalyani A Comprehensive Review on Novel Liposomal Methodologies, Commercial Formulations, Clinical Trials and Patents |
title | A Comprehensive Review on Novel Liposomal Methodologies, Commercial Formulations, Clinical Trials and Patents |
title_full | A Comprehensive Review on Novel Liposomal Methodologies, Commercial Formulations, Clinical Trials and Patents |
title_fullStr | A Comprehensive Review on Novel Liposomal Methodologies, Commercial Formulations, Clinical Trials and Patents |
title_full_unstemmed | A Comprehensive Review on Novel Liposomal Methodologies, Commercial Formulations, Clinical Trials and Patents |
title_short | A Comprehensive Review on Novel Liposomal Methodologies, Commercial Formulations, Clinical Trials and Patents |
title_sort | comprehensive review on novel liposomal methodologies, commercial formulations, clinical trials and patents |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790012/ https://www.ncbi.nlm.nih.gov/pubmed/35096502 http://dx.doi.org/10.1007/s12668-022-00941-x |
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