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Fitness Effects of Mutations: An Assessment of PROVEAN Predictions Using Mutation Accumulation Data

Predicting fitness in natural populations is a major challenge in biology. It may be possible to leverage fast-accumulating genomic data sets to infer the fitness effects of mutant alleles, allowing evolutionary questions to be addressed in any organism. In this paper, we investigate the utility of...

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Detalles Bibliográficos
Autores principales:	Sandell, Linnea, Sharp, Nathaniel P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790079/ https://www.ncbi.nlm.nih.gov/pubmed/35038732 http://dx.doi.org/10.1093/gbe/evac004

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