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Nanomaterial Technology and Triple Negative Breast Cancer
Triple negative breast cancer (TNBC) is a malignant breast cancer subtype that is prone to progression, with high associated metastasis and five-year mortality rates and an overall poor prognosis. Chemotherapy is usually administered to treat TNBC without additional targeted therapies. Novel nanomat...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790081/ https://www.ncbi.nlm.nih.gov/pubmed/35096628 http://dx.doi.org/10.3389/fonc.2021.828810 |
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author | Hou, Kai Ning, Zeng Chen, Hongbo Wu, Yiping |
author_facet | Hou, Kai Ning, Zeng Chen, Hongbo Wu, Yiping |
author_sort | Hou, Kai |
collection | PubMed |
description | Triple negative breast cancer (TNBC) is a malignant breast cancer subtype that is prone to progression, with high associated metastasis and five-year mortality rates and an overall poor prognosis. Chemotherapy is usually administered to treat TNBC without additional targeted therapies. Novel nanomaterials have a variety of excellent physical and chemical properties and biological functions (including targeting specificity), and contrast agents and drug delivery vectors based on nanotechnology are progressing towards a more accurate and targeted direction. This review discusses the mechanisms of action and prospects for the use of nanotechnology in the treatment of TNBC, thus providing potential new strategies for the diagnosis and treatment of TNBC. |
format | Online Article Text |
id | pubmed-8790081 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-87900812022-01-27 Nanomaterial Technology and Triple Negative Breast Cancer Hou, Kai Ning, Zeng Chen, Hongbo Wu, Yiping Front Oncol Oncology Triple negative breast cancer (TNBC) is a malignant breast cancer subtype that is prone to progression, with high associated metastasis and five-year mortality rates and an overall poor prognosis. Chemotherapy is usually administered to treat TNBC without additional targeted therapies. Novel nanomaterials have a variety of excellent physical and chemical properties and biological functions (including targeting specificity), and contrast agents and drug delivery vectors based on nanotechnology are progressing towards a more accurate and targeted direction. This review discusses the mechanisms of action and prospects for the use of nanotechnology in the treatment of TNBC, thus providing potential new strategies for the diagnosis and treatment of TNBC. Frontiers Media S.A. 2022-01-12 /pmc/articles/PMC8790081/ /pubmed/35096628 http://dx.doi.org/10.3389/fonc.2021.828810 Text en Copyright © 2022 Hou, Ning, Chen and Wu https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Oncology Hou, Kai Ning, Zeng Chen, Hongbo Wu, Yiping Nanomaterial Technology and Triple Negative Breast Cancer |
title | Nanomaterial Technology and Triple Negative Breast Cancer |
title_full | Nanomaterial Technology and Triple Negative Breast Cancer |
title_fullStr | Nanomaterial Technology and Triple Negative Breast Cancer |
title_full_unstemmed | Nanomaterial Technology and Triple Negative Breast Cancer |
title_short | Nanomaterial Technology and Triple Negative Breast Cancer |
title_sort | nanomaterial technology and triple negative breast cancer |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790081/ https://www.ncbi.nlm.nih.gov/pubmed/35096628 http://dx.doi.org/10.3389/fonc.2021.828810 |
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