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Vindoline Attenuates Osteoarthritis Progression Through Suppressing the NF-κB and ERK Pathways in Both Chondrocytes and Subchondral Osteoclasts

Disruption of extracellular matrix (ECM) homeostasis and subchondral bone remodeling play significant roles in osteoarthritis (OA) pathogenesis. Vindoline (Vin), an indole alkaloid extracted from the medicinal plant Catharanthus roseus, possesses anti-inflammatory properties. According to previous s...

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Detalles Bibliográficos
Autores principales:	Zhu, Meisong, Xu, Qiang, Yang, Xinmin, Zhan, Haibo, Zhang, Bin, Liu, Xuqiang, Dai, Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790248/ https://www.ncbi.nlm.nih.gov/pubmed/35095488 http://dx.doi.org/10.3389/fphar.2021.764598

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