Literature review of the mechanisms of acute kidney injury secondary to acute liver injury

People exposed to liver ischaemia reperfusion (IR) injury often develop acute kidney injury and the combination is associated with significant morbidity and mortality. Molecular mediators released by the liver in response to IR injury are the likely cause of acute kidney injury (AKI) in this setting...

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Autores principales: Platt, Esther, Klootwijk, Enriko, Salama, Alan, Davidson, Brian, Robertson, Francis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790308/
https://www.ncbi.nlm.nih.gov/pubmed/35117976
http://dx.doi.org/10.5527/wjn.v11.i1.13
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author Platt, Esther
Klootwijk, Enriko
Salama, Alan
Davidson, Brian
Robertson, Francis
author_facet Platt, Esther
Klootwijk, Enriko
Salama, Alan
Davidson, Brian
Robertson, Francis
author_sort Platt, Esther
collection PubMed
description People exposed to liver ischaemia reperfusion (IR) injury often develop acute kidney injury and the combination is associated with significant morbidity and mortality. Molecular mediators released by the liver in response to IR injury are the likely cause of acute kidney injury (AKI) in this setting, but the mediators have not yet been identified. Identifying the mechanism of injury will allow the identification of therapeutic targets which may modulate both liver IR injury and AKI following liver IR injury.
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spelling pubmed-87903082022-02-02 Literature review of the mechanisms of acute kidney injury secondary to acute liver injury Platt, Esther Klootwijk, Enriko Salama, Alan Davidson, Brian Robertson, Francis World J Nephrol Review People exposed to liver ischaemia reperfusion (IR) injury often develop acute kidney injury and the combination is associated with significant morbidity and mortality. Molecular mediators released by the liver in response to IR injury are the likely cause of acute kidney injury (AKI) in this setting, but the mediators have not yet been identified. Identifying the mechanism of injury will allow the identification of therapeutic targets which may modulate both liver IR injury and AKI following liver IR injury. Baishideng Publishing Group Inc 2022-01-25 2022-01-25 /pmc/articles/PMC8790308/ /pubmed/35117976 http://dx.doi.org/10.5527/wjn.v11.i1.13 Text en ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
spellingShingle Review
Platt, Esther
Klootwijk, Enriko
Salama, Alan
Davidson, Brian
Robertson, Francis
Literature review of the mechanisms of acute kidney injury secondary to acute liver injury
title Literature review of the mechanisms of acute kidney injury secondary to acute liver injury
title_full Literature review of the mechanisms of acute kidney injury secondary to acute liver injury
title_fullStr Literature review of the mechanisms of acute kidney injury secondary to acute liver injury
title_full_unstemmed Literature review of the mechanisms of acute kidney injury secondary to acute liver injury
title_short Literature review of the mechanisms of acute kidney injury secondary to acute liver injury
title_sort literature review of the mechanisms of acute kidney injury secondary to acute liver injury
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790308/
https://www.ncbi.nlm.nih.gov/pubmed/35117976
http://dx.doi.org/10.5527/wjn.v11.i1.13
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