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Laparoscopic Kasai portoenterostomy can be a standard surgical procedure for treatment of biliary atresia
BACKGROUND: Biliary atresia (BA) is a rare pediatric disease. AIM: To compare the outcomes of laparoscopic portoenterostomy (Lap-PE) with those of laparotomy (Open-PE) at a single institution. METHODS: The surgical outcomes of PE were retrospectively analyzed for patients with a non-correctable type...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790325/ https://www.ncbi.nlm.nih.gov/pubmed/35126863 http://dx.doi.org/10.4240/wjgs.v14.i1.56 |
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author | Shirota, Chiyoe Hinoki, Akinari Tainaka, Takahisa Sumida, Wataru Kinoshita, Fumie Yokota, Kazuki Makita, Satoshi Amano, Hizuru Nakagawa, Yoichi Uchida, Hiroo |
author_facet | Shirota, Chiyoe Hinoki, Akinari Tainaka, Takahisa Sumida, Wataru Kinoshita, Fumie Yokota, Kazuki Makita, Satoshi Amano, Hizuru Nakagawa, Yoichi Uchida, Hiroo |
author_sort | Shirota, Chiyoe |
collection | PubMed |
description | BACKGROUND: Biliary atresia (BA) is a rare pediatric disease. AIM: To compare the outcomes of laparoscopic portoenterostomy (Lap-PE) with those of laparotomy (Open-PE) at a single institution. METHODS: The surgical outcomes of PE were retrospectively analyzed for patients with a non-correctable type of BA from 2003 to 2020. RESULTS: Throughout the assessment period, 119 patients received PE for BA treatment, including 66 Open-PE and 53 Lap-PE cases. Although the operation duration was longer (medians: for Open-PE, 242 min; for Lap-PE, 341 min; P < 0.001), blood loss was considerably less (medians: for Open-PE, 52 mL; for Lap-PE, 24 mL; P < 0.001) in the Lap-PE group than in the Open-PE group. The postoperative recovery of the Lap-PE group was more favorable; specifically, both times to resume oral intake and drain removal were significantly shorter in the Lap-PE group. Complete resolution of jaundice was observed in 45 Open-PE cases and 42 Lap-PE cases, with no statistically significant difference (P = 0.176). Native liver survival rates were >80% for both groups for the first half year post surgery, followed by a gradual decrease with time; there were no statistically significant differences in the native liver survival rates for any durations assessed. CONCLUSION: Lap-PE could be a standard therapy for BA. |
format | Online Article Text |
id | pubmed-8790325 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Baishideng Publishing Group Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-87903252022-02-04 Laparoscopic Kasai portoenterostomy can be a standard surgical procedure for treatment of biliary atresia Shirota, Chiyoe Hinoki, Akinari Tainaka, Takahisa Sumida, Wataru Kinoshita, Fumie Yokota, Kazuki Makita, Satoshi Amano, Hizuru Nakagawa, Yoichi Uchida, Hiroo World J Gastrointest Surg Retrospective Study BACKGROUND: Biliary atresia (BA) is a rare pediatric disease. AIM: To compare the outcomes of laparoscopic portoenterostomy (Lap-PE) with those of laparotomy (Open-PE) at a single institution. METHODS: The surgical outcomes of PE were retrospectively analyzed for patients with a non-correctable type of BA from 2003 to 2020. RESULTS: Throughout the assessment period, 119 patients received PE for BA treatment, including 66 Open-PE and 53 Lap-PE cases. Although the operation duration was longer (medians: for Open-PE, 242 min; for Lap-PE, 341 min; P < 0.001), blood loss was considerably less (medians: for Open-PE, 52 mL; for Lap-PE, 24 mL; P < 0.001) in the Lap-PE group than in the Open-PE group. The postoperative recovery of the Lap-PE group was more favorable; specifically, both times to resume oral intake and drain removal were significantly shorter in the Lap-PE group. Complete resolution of jaundice was observed in 45 Open-PE cases and 42 Lap-PE cases, with no statistically significant difference (P = 0.176). Native liver survival rates were >80% for both groups for the first half year post surgery, followed by a gradual decrease with time; there were no statistically significant differences in the native liver survival rates for any durations assessed. CONCLUSION: Lap-PE could be a standard therapy for BA. Baishideng Publishing Group Inc 2022-01-27 2022-01-27 /pmc/articles/PMC8790325/ /pubmed/35126863 http://dx.doi.org/10.4240/wjgs.v14.i1.56 Text en ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
spellingShingle | Retrospective Study Shirota, Chiyoe Hinoki, Akinari Tainaka, Takahisa Sumida, Wataru Kinoshita, Fumie Yokota, Kazuki Makita, Satoshi Amano, Hizuru Nakagawa, Yoichi Uchida, Hiroo Laparoscopic Kasai portoenterostomy can be a standard surgical procedure for treatment of biliary atresia |
title | Laparoscopic Kasai portoenterostomy can be a standard surgical procedure for treatment of biliary atresia |
title_full | Laparoscopic Kasai portoenterostomy can be a standard surgical procedure for treatment of biliary atresia |
title_fullStr | Laparoscopic Kasai portoenterostomy can be a standard surgical procedure for treatment of biliary atresia |
title_full_unstemmed | Laparoscopic Kasai portoenterostomy can be a standard surgical procedure for treatment of biliary atresia |
title_short | Laparoscopic Kasai portoenterostomy can be a standard surgical procedure for treatment of biliary atresia |
title_sort | laparoscopic kasai portoenterostomy can be a standard surgical procedure for treatment of biliary atresia |
topic | Retrospective Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790325/ https://www.ncbi.nlm.nih.gov/pubmed/35126863 http://dx.doi.org/10.4240/wjgs.v14.i1.56 |
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