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Laparoscopic Kasai portoenterostomy can be a standard surgical procedure for treatment of biliary atresia

BACKGROUND: Biliary atresia (BA) is a rare pediatric disease. AIM: To compare the outcomes of laparoscopic portoenterostomy (Lap-PE) with those of laparotomy (Open-PE) at a single institution. METHODS: The surgical outcomes of PE were retrospectively analyzed for patients with a non-correctable type...

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Autores principales: Shirota, Chiyoe, Hinoki, Akinari, Tainaka, Takahisa, Sumida, Wataru, Kinoshita, Fumie, Yokota, Kazuki, Makita, Satoshi, Amano, Hizuru, Nakagawa, Yoichi, Uchida, Hiroo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790325/
https://www.ncbi.nlm.nih.gov/pubmed/35126863
http://dx.doi.org/10.4240/wjgs.v14.i1.56
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author Shirota, Chiyoe
Hinoki, Akinari
Tainaka, Takahisa
Sumida, Wataru
Kinoshita, Fumie
Yokota, Kazuki
Makita, Satoshi
Amano, Hizuru
Nakagawa, Yoichi
Uchida, Hiroo
author_facet Shirota, Chiyoe
Hinoki, Akinari
Tainaka, Takahisa
Sumida, Wataru
Kinoshita, Fumie
Yokota, Kazuki
Makita, Satoshi
Amano, Hizuru
Nakagawa, Yoichi
Uchida, Hiroo
author_sort Shirota, Chiyoe
collection PubMed
description BACKGROUND: Biliary atresia (BA) is a rare pediatric disease. AIM: To compare the outcomes of laparoscopic portoenterostomy (Lap-PE) with those of laparotomy (Open-PE) at a single institution. METHODS: The surgical outcomes of PE were retrospectively analyzed for patients with a non-correctable type of BA from 2003 to 2020. RESULTS: Throughout the assessment period, 119 patients received PE for BA treatment, including 66 Open-PE and 53 Lap-PE cases. Although the operation duration was longer (medians: for Open-PE, 242 min; for Lap-PE, 341 min; P < 0.001), blood loss was considerably less (medians: for Open-PE, 52 mL; for Lap-PE, 24 mL; P < 0.001) in the Lap-PE group than in the Open-PE group. The postoperative recovery of the Lap-PE group was more favorable; specifically, both times to resume oral intake and drain removal were significantly shorter in the Lap-PE group. Complete resolution of jaundice was observed in 45 Open-PE cases and 42 Lap-PE cases, with no statistically significant difference (P = 0.176). Native liver survival rates were >80% for both groups for the first half year post surgery, followed by a gradual decrease with time; there were no statistically significant differences in the native liver survival rates for any durations assessed. CONCLUSION: Lap-PE could be a standard therapy for BA.
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spelling pubmed-87903252022-02-04 Laparoscopic Kasai portoenterostomy can be a standard surgical procedure for treatment of biliary atresia Shirota, Chiyoe Hinoki, Akinari Tainaka, Takahisa Sumida, Wataru Kinoshita, Fumie Yokota, Kazuki Makita, Satoshi Amano, Hizuru Nakagawa, Yoichi Uchida, Hiroo World J Gastrointest Surg Retrospective Study BACKGROUND: Biliary atresia (BA) is a rare pediatric disease. AIM: To compare the outcomes of laparoscopic portoenterostomy (Lap-PE) with those of laparotomy (Open-PE) at a single institution. METHODS: The surgical outcomes of PE were retrospectively analyzed for patients with a non-correctable type of BA from 2003 to 2020. RESULTS: Throughout the assessment period, 119 patients received PE for BA treatment, including 66 Open-PE and 53 Lap-PE cases. Although the operation duration was longer (medians: for Open-PE, 242 min; for Lap-PE, 341 min; P < 0.001), blood loss was considerably less (medians: for Open-PE, 52 mL; for Lap-PE, 24 mL; P < 0.001) in the Lap-PE group than in the Open-PE group. The postoperative recovery of the Lap-PE group was more favorable; specifically, both times to resume oral intake and drain removal were significantly shorter in the Lap-PE group. Complete resolution of jaundice was observed in 45 Open-PE cases and 42 Lap-PE cases, with no statistically significant difference (P = 0.176). Native liver survival rates were >80% for both groups for the first half year post surgery, followed by a gradual decrease with time; there were no statistically significant differences in the native liver survival rates for any durations assessed. CONCLUSION: Lap-PE could be a standard therapy for BA. Baishideng Publishing Group Inc 2022-01-27 2022-01-27 /pmc/articles/PMC8790325/ /pubmed/35126863 http://dx.doi.org/10.4240/wjgs.v14.i1.56 Text en ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
spellingShingle Retrospective Study
Shirota, Chiyoe
Hinoki, Akinari
Tainaka, Takahisa
Sumida, Wataru
Kinoshita, Fumie
Yokota, Kazuki
Makita, Satoshi
Amano, Hizuru
Nakagawa, Yoichi
Uchida, Hiroo
Laparoscopic Kasai portoenterostomy can be a standard surgical procedure for treatment of biliary atresia
title Laparoscopic Kasai portoenterostomy can be a standard surgical procedure for treatment of biliary atresia
title_full Laparoscopic Kasai portoenterostomy can be a standard surgical procedure for treatment of biliary atresia
title_fullStr Laparoscopic Kasai portoenterostomy can be a standard surgical procedure for treatment of biliary atresia
title_full_unstemmed Laparoscopic Kasai portoenterostomy can be a standard surgical procedure for treatment of biliary atresia
title_short Laparoscopic Kasai portoenterostomy can be a standard surgical procedure for treatment of biliary atresia
title_sort laparoscopic kasai portoenterostomy can be a standard surgical procedure for treatment of biliary atresia
topic Retrospective Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790325/
https://www.ncbi.nlm.nih.gov/pubmed/35126863
http://dx.doi.org/10.4240/wjgs.v14.i1.56
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