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Multiple roles of ribosomal antimicrobial peptides in tackling global antimicrobial resistance
In the last century, conventional antibiotics have played a significant role in global healthcare. Antibiotics support the body in controlling bacterial infection and simultaneously increase the tendency of drug resistance. Consequently, there is a severe concern regarding the regression of the anti...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790363/ https://www.ncbi.nlm.nih.gov/pubmed/35116161 http://dx.doi.org/10.1098/rsos.211583 |
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author | Luong, Huy Xuan Ngan, Hoa Doan Thi Phuong, Hai Bui Quoc, Thang Nguyen Tung, Truong Thanh |
author_facet | Luong, Huy Xuan Ngan, Hoa Doan Thi Phuong, Hai Bui Quoc, Thang Nguyen Tung, Truong Thanh |
author_sort | Luong, Huy Xuan |
collection | PubMed |
description | In the last century, conventional antibiotics have played a significant role in global healthcare. Antibiotics support the body in controlling bacterial infection and simultaneously increase the tendency of drug resistance. Consequently, there is a severe concern regarding the regression of the antibiotic era. Despite the use of antibiotics, host defence systems are vital in fighting infectious diseases. In fact, the expression of ribosomal antimicrobial peptides (AMPs) has been crucial in the evolution of innate host defences and has been irreplaceable to date. Therefore, this valuable source is considered to have great potential in tackling the antimicrobial resistance (AMR) crisis. Furthermore, the possibility of bacterial resistance to AMPs has been intensively investigated. Here, we summarize all aspects related to the multiple applications of ribosomal AMPs and their derivatives in combating AMR. |
format | Online Article Text |
id | pubmed-8790363 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | The Royal Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-87903632022-02-02 Multiple roles of ribosomal antimicrobial peptides in tackling global antimicrobial resistance Luong, Huy Xuan Ngan, Hoa Doan Thi Phuong, Hai Bui Quoc, Thang Nguyen Tung, Truong Thanh R Soc Open Sci Chemistry In the last century, conventional antibiotics have played a significant role in global healthcare. Antibiotics support the body in controlling bacterial infection and simultaneously increase the tendency of drug resistance. Consequently, there is a severe concern regarding the regression of the antibiotic era. Despite the use of antibiotics, host defence systems are vital in fighting infectious diseases. In fact, the expression of ribosomal antimicrobial peptides (AMPs) has been crucial in the evolution of innate host defences and has been irreplaceable to date. Therefore, this valuable source is considered to have great potential in tackling the antimicrobial resistance (AMR) crisis. Furthermore, the possibility of bacterial resistance to AMPs has been intensively investigated. Here, we summarize all aspects related to the multiple applications of ribosomal AMPs and their derivatives in combating AMR. The Royal Society 2022-01-26 /pmc/articles/PMC8790363/ /pubmed/35116161 http://dx.doi.org/10.1098/rsos.211583 Text en © 2022 The Authors. https://creativecommons.org/licenses/by/4.0/Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, provided the original author and source are credited. |
spellingShingle | Chemistry Luong, Huy Xuan Ngan, Hoa Doan Thi Phuong, Hai Bui Quoc, Thang Nguyen Tung, Truong Thanh Multiple roles of ribosomal antimicrobial peptides in tackling global antimicrobial resistance |
title | Multiple roles of ribosomal antimicrobial peptides in tackling global antimicrobial resistance |
title_full | Multiple roles of ribosomal antimicrobial peptides in tackling global antimicrobial resistance |
title_fullStr | Multiple roles of ribosomal antimicrobial peptides in tackling global antimicrobial resistance |
title_full_unstemmed | Multiple roles of ribosomal antimicrobial peptides in tackling global antimicrobial resistance |
title_short | Multiple roles of ribosomal antimicrobial peptides in tackling global antimicrobial resistance |
title_sort | multiple roles of ribosomal antimicrobial peptides in tackling global antimicrobial resistance |
topic | Chemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790363/ https://www.ncbi.nlm.nih.gov/pubmed/35116161 http://dx.doi.org/10.1098/rsos.211583 |
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