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Comprehensive summary of mitochondrial DNA alterations in the postmortem human brain: A systematic review

BACKGROUND: Mitochondrial DNA (mtDNA) encodes 37 genes necessary for synthesizing 13 essential subunits of the oxidative phosphorylation system. mtDNA alterations are known to cause mitochondrial disease (MitD), a clinically heterogeneous group of disorders that often present with neuropsychiatric s...

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Detalles Bibliográficos
Autores principales:	Valiente-Pallejà, Alba, Tortajada, Juan, Bulduk, Bengisu K., Vilella, Elisabet, Garrabou, Glòria, Muntané, Gerard, Martorell, Lourdes
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790490/ https://www.ncbi.nlm.nih.gov/pubmed/35085849 http://dx.doi.org/10.1016/j.ebiom.2022.103815

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