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The Kynurenine/Tryptophan Ratio Is a Sensitive Biomarker for the Diagnosis of Pediatric Tuberculosis Among Indian Children

OBJECTIVES: Pediatric tuberculosis (TB) remains difficult to diagnose. The plasma kynurenine to tryptophan ratio (K/T ratio) is a potential biomarker for TB diagnosis and treatment response but has not been assessed in children. METHODS: We performed a targeted diagnostic accuracy analysis of four b...

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Detalles Bibliográficos
Autores principales: Tornheim, Jeffrey A., Paradkar, Mandar, Zhao, Henry, Kulkarni, Vandana, Pradhan, Neeta, Kinikar, Aarti, Kagal, Anju, Gupte, Nikhil, Mave, Vidya, Gupta, Amita, Karakousis, Petros C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790563/
https://www.ncbi.nlm.nih.gov/pubmed/35095848
http://dx.doi.org/10.3389/fimmu.2021.774043