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Analyzing the human gut mycobiome – A short guide for beginners

The human body is a dynamic ecosystem consisting of millions of microbes which are often comprised under the term microbiome. Compared to bacteria, which count for the overwhelming majority of the microbiome, the number of human-associated fungi is small and often underestimated. Nonetheless, they c...

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Detalles Bibliográficos
Autores principales: Thielemann, Nadja, Herz, Michaela, Kurzai, Oliver, Martin, Ronny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790610/
https://www.ncbi.nlm.nih.gov/pubmed/35116136
http://dx.doi.org/10.1016/j.csbj.2022.01.008
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author Thielemann, Nadja
Herz, Michaela
Kurzai, Oliver
Martin, Ronny
author_facet Thielemann, Nadja
Herz, Michaela
Kurzai, Oliver
Martin, Ronny
author_sort Thielemann, Nadja
collection PubMed
description The human body is a dynamic ecosystem consisting of millions of microbes which are often comprised under the term microbiome. Compared to bacteria, which count for the overwhelming majority of the microbiome, the number of human-associated fungi is small and often underestimated. Nonetheless, they can be found in different host niches such as the gut, the oral cavity and the skin. The fungal community has several potential roles in health and disease of the human host. In this review we will focus on intestinal fungi and their interaction with the host as well as bacteria. We also summarize technical challenges and possible biases researchers must be aware of when conducting mycobiome analysis.
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spelling pubmed-87906102022-02-02 Analyzing the human gut mycobiome – A short guide for beginners Thielemann, Nadja Herz, Michaela Kurzai, Oliver Martin, Ronny Comput Struct Biotechnol J Review Article The human body is a dynamic ecosystem consisting of millions of microbes which are often comprised under the term microbiome. Compared to bacteria, which count for the overwhelming majority of the microbiome, the number of human-associated fungi is small and often underestimated. Nonetheless, they can be found in different host niches such as the gut, the oral cavity and the skin. The fungal community has several potential roles in health and disease of the human host. In this review we will focus on intestinal fungi and their interaction with the host as well as bacteria. We also summarize technical challenges and possible biases researchers must be aware of when conducting mycobiome analysis. Research Network of Computational and Structural Biotechnology 2022-01-19 /pmc/articles/PMC8790610/ /pubmed/35116136 http://dx.doi.org/10.1016/j.csbj.2022.01.008 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review Article
Thielemann, Nadja
Herz, Michaela
Kurzai, Oliver
Martin, Ronny
Analyzing the human gut mycobiome – A short guide for beginners
title Analyzing the human gut mycobiome – A short guide for beginners
title_full Analyzing the human gut mycobiome – A short guide for beginners
title_fullStr Analyzing the human gut mycobiome – A short guide for beginners
title_full_unstemmed Analyzing the human gut mycobiome – A short guide for beginners
title_short Analyzing the human gut mycobiome – A short guide for beginners
title_sort analyzing the human gut mycobiome – a short guide for beginners
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790610/
https://www.ncbi.nlm.nih.gov/pubmed/35116136
http://dx.doi.org/10.1016/j.csbj.2022.01.008
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