Mesenchymal Stem Cells Derived Extracellular Vesicles Alleviate Traumatic Hemorrhagic Shock Induced Hepatic Injury via IL-10/PTPN22-Mediated M2 Kupffer Cell Polarization

Traumatic hemorrhagic shock (THS) is a major cause of mortality and morbidity worldwide in severely injured patients. Mesenchymal stem cells (MSCs) possess immunomodulatory properties and tissue repair potential mainly through a paracrine pathway mediated by MSC-derived extracellular vesicles (MSC-E...

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Detalles Bibliográficos
Autores principales: Zhang, Yunwei, Zhang, Xiaofei, Zhang, Hongji, Song, Peng, Pan, Wenming, Xu, Peng, Wang, Guoliang, Hu, Ping, Wang, Zixuan, Huang, Kunpeng, Zhang, Xiaodong, Wang, Hui, Zhang, Jinxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790700/
https://www.ncbi.nlm.nih.gov/pubmed/35095903
http://dx.doi.org/10.3389/fimmu.2021.811164

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