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Dynamics of 5R-Tg Base Flipping in DNA Duplexes Based on Simulations—Agreement with Experiments and Beyond
[Image: see text] Damaged or mismatched DNA bases are normally thought to be able to flip out of the helical stack, providing enzymes with access to the faulty genetic information otherwise hidden inside the helix. Thymine glycol (Tg) is one of the most common products of nucleic acid damage. Howeve...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790752/ https://www.ncbi.nlm.nih.gov/pubmed/34994562 http://dx.doi.org/10.1021/acs.jcim.1c01169 |