Universal encoding of next generation DNA-encoded chemical libraries

DNA-encoded chemical libraries (DELs) are useful tools for the discovery of small molecule ligands to protein targets of pharmaceutical interest. Compared with single-pharmacophore DELs, dual-pharmacophore DELs simultaneously display two chemical moieties on both DNA strands, and allow for the const...

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Detalles Bibliográficos
Autores principales: Plais, Louise, Lessing, Alice, Keller, Michelle, Martinelli, Adriano, Oehler, Sebastian, Bassi, Gabriele, Neri, Dario, Scheuermann, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790773/
https://www.ncbi.nlm.nih.gov/pubmed/35211261
http://dx.doi.org/10.1039/d1sc05721a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790773/
https://www.ncbi.nlm.nih.gov/pubmed/35211261
http://dx.doi.org/10.1039/d1sc05721a

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