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Ortho-selective C–H arylation of phenols with N-carboxyindoles under Brønsted acid- or Cu(i)-catalysis

Control over chemo- and regioselectivity is a critical issue in the heterobiaryl synthesis via C–H oxidative coupling. To address this challenge, a strategy to invert the normal polarity of indoles in the heterobiaryl coupling was developed. With N-carboxyindoles as umpoled indoles, an exclusively o...

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Detalles Bibliográficos
Autores principales: Nguyen, Nguyen H., Oh, Soo Min, Park, Cheol-Min, Shin, Seunghoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790926/
https://www.ncbi.nlm.nih.gov/pubmed/35211284
http://dx.doi.org/10.1039/d1sc06157g