Reduced growth rate of aged muscle stem cells is associated with impaired mechanosensitivity

Aging-associated muscle wasting and impaired regeneration are caused by deficiencies in muscle stem cell (MuSC) number and function. We postulated that aged MuSCs are intrinsically impaired in their responsiveness to omnipresent mechanical cues through alterations in MuSC morphology, mechanical prop...

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Detalles Bibliográficos
Autores principales: Haroon, Mohammad, Boers, Heleen E., Bakker, Astrid D., Bloks, Niek G.C., Hoogaars, Willem M.H., Giordani, Lorenzo, Musters, René J.P., Deldicque, Louise, Koppo, Katrien, Le Grand, Fabien, Klein-Nulend, Jenneke, Jaspers, Richard T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791224/
https://www.ncbi.nlm.nih.gov/pubmed/35023852
http://dx.doi.org/10.18632/aging.203830

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