Protective Efficacy of Gastrointestinal SARS-CoV-2 Delivery against Intranasal and Intratracheal SARS-CoV-2 Challenge in Rhesus Macaques

Live oral vaccines have been explored for their protective efficacy against respiratory viruses, particularly for adenovirus serotypes 4 and 7. The potential of a live oral vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), however, remains unclear. In this study, we asses...

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Detalles Bibliográficos
Autores principales: Yu, Jingyou, Collins, Natalie D., Mercado, Noe B., McMahan, Katherine, Chandrashekar, Abishek, Liu, Jinyan, Anioke, Tochi, Chang, Aiquan, Giffin, Victoria M., Hope, David L., Sellers, Daniel, Nampanya, Felix, Gardner, Sarah, Barrett, Julia, Wan, Huahua, Velasco, Jason, Teow, Elyse, Cook, Anthony, Van Ry, Alex, Pessaint, Laurent, Andersen, Hanne, Lewis, Mark G., Hofer, Christian, Burke, Donald S., Barkei, Erica K., King, Hannah A. D., Subra, Caroline, Bolton, Diane, Modjarrad, Kayvon, Michael, Nelson L., Barouch, Dan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791250/
https://www.ncbi.nlm.nih.gov/pubmed/34705557
http://dx.doi.org/10.1128/JVI.01599-21

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