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BST2 Suppresses LINE-1 Retrotransposition by Reducing the Promoter Activity of LINE-1 5′ UTR

Endogenous retrotransposons are considered the “molecular fossils” of ancient retroviral insertions. Several studies have indicated that host factors restrict both retroviruses and retrotransposons through different mechanisms. Type 1 long interspersed elements (LINE-1 or L1) are the only active ret...

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Detalles Bibliográficos
Autores principales:	Zhao, Yifei, Du, Juan, Wang, Yu, Wang, Qing, Wang, Shaohua, Zhao, Ke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Gene Delivery
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791264/ https://www.ncbi.nlm.nih.gov/pubmed/34730388 http://dx.doi.org/10.1128/JVI.01610-21

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