Two Distinct Mechanisms Leading to Loss of Virological Control in the Rare Group of Antiretroviral Therapy-Naive, Transiently Aviremic Children Living with HIV

HIV-specific CD8(+) T cells play a central role in immune control of adult HIV, but their contribution in pediatric infection is less well characterized. Previously, we identified a group of ART-naive children with persistently undetectable plasma viremia, termed “elite controllers,” and a second gr...

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Detalles Bibliográficos
Autores principales: Vieira, Vinicius A., Adland, Emily, Grayson, Nicholas E., Csala, Anna, Richards, Fa’eeda, Dacon, Cherrelle, Athavale, Rohin, Tsai, Ming-Han, D’Souza, Reena, Muenchhoff, Maximilian, Bonsall, David, Jooste, Pieter, Goulder, Philip J. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Pathogenesis and Immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791270/
https://www.ncbi.nlm.nih.gov/pubmed/34757843
http://dx.doi.org/10.1128/JVI.01535-21

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