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Racial disparities in cardiac transplantation: Chronological perspective and outcomes

BACKGROUND: The objective of this study was to evaluate annual heart transplant volumes and 3-year post-transplant outcomes since establishment of United Network for Organ Sharing (UNOS) database stratified by race. METHODS: The UNOS thoracic transplant database was evaluated for adult patients sinc...

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Autores principales: Trivedi, Jaimin R., Pahwa, Siddharth V., Whitehouse, Katherine R., Ceremuga, Bradley M., Slaughter, Mark S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791525/
https://www.ncbi.nlm.nih.gov/pubmed/35081136
http://dx.doi.org/10.1371/journal.pone.0262945
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author Trivedi, Jaimin R.
Pahwa, Siddharth V.
Whitehouse, Katherine R.
Ceremuga, Bradley M.
Slaughter, Mark S.
author_facet Trivedi, Jaimin R.
Pahwa, Siddharth V.
Whitehouse, Katherine R.
Ceremuga, Bradley M.
Slaughter, Mark S.
author_sort Trivedi, Jaimin R.
collection PubMed
description BACKGROUND: The objective of this study was to evaluate annual heart transplant volumes and 3-year post-transplant outcomes since establishment of United Network for Organ Sharing (UNOS) database stratified by race. METHODS: The UNOS thoracic transplant database was evaluated for adult patients since 1987. The available database was then stratified by Race: Black, White and Other and era of transplant: group 1(1987–1991), group 2(1992–1996), group 3(1997–2001), group 4(2002–2006), group 5(2007–2011), group 6(2012–2016) and group 7(2017 and later). Demographic and clinical factors were evaluated. RESULTS: A total of 105,266 adults have been listed since 1987 and 67,824 have been transplanted. Of the transplanted patients 11,235 were Black, 48,786 White and 6803 were of Other race. The proportion of Black patients listed increased from 7% in 1987 to 13.4% in 1999 and 25% in 2019 and those transplanted increased from 5% in 1987 to 13.4% in 2001 and 26% in 2019. The survival of Black patients gradually improved. CONCLUSION: Historically, fewer Black patients received cardiac transplantation however, their access gradually improved over the years and account for over 25% of cardiac transplantations performed in recent years. The historically poor survival of Black patients has recently improved and became comparable to the rest.
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spelling pubmed-87915252022-01-27 Racial disparities in cardiac transplantation: Chronological perspective and outcomes Trivedi, Jaimin R. Pahwa, Siddharth V. Whitehouse, Katherine R. Ceremuga, Bradley M. Slaughter, Mark S. PLoS One Research Article BACKGROUND: The objective of this study was to evaluate annual heart transplant volumes and 3-year post-transplant outcomes since establishment of United Network for Organ Sharing (UNOS) database stratified by race. METHODS: The UNOS thoracic transplant database was evaluated for adult patients since 1987. The available database was then stratified by Race: Black, White and Other and era of transplant: group 1(1987–1991), group 2(1992–1996), group 3(1997–2001), group 4(2002–2006), group 5(2007–2011), group 6(2012–2016) and group 7(2017 and later). Demographic and clinical factors were evaluated. RESULTS: A total of 105,266 adults have been listed since 1987 and 67,824 have been transplanted. Of the transplanted patients 11,235 were Black, 48,786 White and 6803 were of Other race. The proportion of Black patients listed increased from 7% in 1987 to 13.4% in 1999 and 25% in 2019 and those transplanted increased from 5% in 1987 to 13.4% in 2001 and 26% in 2019. The survival of Black patients gradually improved. CONCLUSION: Historically, fewer Black patients received cardiac transplantation however, their access gradually improved over the years and account for over 25% of cardiac transplantations performed in recent years. The historically poor survival of Black patients has recently improved and became comparable to the rest. Public Library of Science 2022-01-26 /pmc/articles/PMC8791525/ /pubmed/35081136 http://dx.doi.org/10.1371/journal.pone.0262945 Text en © 2022 Trivedi et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Trivedi, Jaimin R.
Pahwa, Siddharth V.
Whitehouse, Katherine R.
Ceremuga, Bradley M.
Slaughter, Mark S.
Racial disparities in cardiac transplantation: Chronological perspective and outcomes
title Racial disparities in cardiac transplantation: Chronological perspective and outcomes
title_full Racial disparities in cardiac transplantation: Chronological perspective and outcomes
title_fullStr Racial disparities in cardiac transplantation: Chronological perspective and outcomes
title_full_unstemmed Racial disparities in cardiac transplantation: Chronological perspective and outcomes
title_short Racial disparities in cardiac transplantation: Chronological perspective and outcomes
title_sort racial disparities in cardiac transplantation: chronological perspective and outcomes
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791525/
https://www.ncbi.nlm.nih.gov/pubmed/35081136
http://dx.doi.org/10.1371/journal.pone.0262945
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