Cargando…

MiR-26a Reduces Inflammatory Responses via Inhibition of PGE2 Production by Targeting COX-2

MicroRNAs are small non-coding RNA regulatory molecules that play an important role in the development and function of immune cells. MicroRNA-26a (miR-26a) exhibits anti-inflammatory immune effects on immune cells. However, the exact mechanism by which miR-26a plays an anti-inflammatory role remains...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Ting, Wang, Peng, Wu, Yuxia, Zhong, Jingbo, Chen, Qingshu, Wang, Daimei, Chen, Hong, Hu, Shengfeng, Wu, Qiongshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791555/ https://www.ncbi.nlm.nih.gov/pubmed/35083625 http://dx.doi.org/10.1007/s10753-022-01631-2

Ejemplares similares

COX-2-PGE(2)-EPs in gynecological cancers
por: Ye, Yao, et al.
Publicado: (2020)

Growth and adherence of Staphylococcus aureus were enhanced through the PGE(2) produced by the activated COX-2/PGE(2) pathway of infected oral epithelial cells
por: Wang, Yuxia, et al.
Publicado: (2017)

Orientin, a Bio-Flavonoid from Trigonella hamosa L., Regulates COX-2/PGE-2 in A549 Cell Lines via miR-26b and miR-146a
por: Khalil, Hany Ezzat, et al.
Publicado: (2022)

miR-144 and targets, c-fos and cyclooxygenase-2 (COX2), modulate synthesis of PGE2 in the amnion during pregnancy and labor
por: Li, Huanan, et al.
Publicado: (2016)

Regulated Expression of PTPRJ by COX-2/PGE(2) Axis in Endothelial Cells
por: Xu, Xiaobing, et al.
Publicado: (2014)

IL-33 facilitates proliferation of colorectal cancer dependent on COX2/PGE(2)
por: Li, Yongkui, et al.
Publicado: (2018)

miR-26b Mimic Inhibits Glioma Proliferation In Vitro and In Vivo Suppressing COX-2 Expression
por: Chen, Zheng-Gang, et al.
Publicado: (2019)

Involvement of COX-2/PGE(2) signalling in hypoxia-induced angiogenic response in endothelial cells
por: Zhao, Lixing, et al.
Publicado: (2012)

Correction to: IL-33 facilitates proliferation of colorectal cancer dependent on COX2/PGE(2)
por: Li, Yongkui, et al.
Publicado: (2020)

COX-2/PGE2 upregulation contributes to the chromosome 17p-deleted lymphoma
por: Qi, Lu, et al.
Publicado: (2023)

miR-137 boosts the neuroprotective effect of endothelial progenitor cell-derived exosomes in oxyhemoglobin-treated SH-SY5Y cells partially via COX2/PGE2 pathway
por: Li, Yuchen, et al.
Publicado: (2020)

Targeting of the COX-2/PGE2 axis enhances the antitumor activity of T7 peptide in vitro and in vivo
por: Yang, Jianrong, et al.
Publicado: (2021)

Formononetin inhibits enterovirus 71 replication by regulating COX- 2/PGE(2) expression
por: Wang, Huiqiang, et al.
Publicado: (2015)

Pleiotropic effects of the COX-2/PGE2 axis in the glioblastoma tumor microenvironment
por: Dean, Phillip T., et al.
Publicado: (2023)

Finasteride Enhances the Generation of Human Myeloid-Derived Suppressor Cells by Up-Regulating the COX2/PGE(2) Pathway
por: Zhang, Shaoying, et al.
Publicado: (2016)

ERK1/2/COX-2/PGE(2) signaling pathway mediates GPR91-dependent VEGF release in streptozotocin-induced diabetes
por: Li, Tingting, et al.
Publicado: (2014)

Role of COX-2/PGE2 Mediated Inflammation in Oral Squamous Cell Carcinoma
por: Nasry, Walaa Hamed Shaker, et al.
Publicado: (2018)

Improving VEGF-targeted therapies through inhibition of COX-2/PGE(2) signaling
por: Xu, Lihong, et al.
Publicado: (2014)

COX2 regulates senescence secretome composition and senescence surveillance through PGE(2)
por: Gonçalves, Susana, et al.
Publicado: (2021)

Dedifferentiation of Human Cardiac Myofibroblasts Is Independent of Activation of COX-2/PGE(2) Pathway
por: Luu, Vy Tran, et al.
Publicado: (2022)

D-dopachrome tautomerase activates COX2/PGE(2) pathway of astrocytes to mediate inflammation following spinal cord injury
por: Ji, Huiyuan, et al.
Publicado: (2021)

Mesenchymal stem cells inhibited the differentiation of MDSCs via COX2/PGE2 in experimental sialadenitis
por: Qi, Jingjing, et al.
Publicado: (2020)

Positive acceleration adaptive training attenuates gastric ischemia-reperfusion injury through COX-2 and PGE2 expression
por: Chen, Ying, et al.
Publicado: (2019)

Vitamin D stimulates miR-26b-5p to inhibit placental COX-2 expression in preeclampsia
por: Cao, Yang, et al.
Publicado: (2021)

MRP4 regulates ENaC-dependent CREB/COX-2/PGE(2) signaling during embryo implantation
por: Chen, Jun-Jiang, et al.
Publicado: (2017)

Involvement of COX-2/PGE(2) Pathway in the Upregulation of MMP-9 Expression in Pancreatic Cancer
por: Bu, Xianmin, et al.
Publicado: (2011)

The Role of COX-2 and PGE2 in the Regulation of Immunomodulation and Other Functions of Mesenchymal Stromal Cells
por: Kulesza, Agnieszka, et al.
Publicado: (2023)

Resveratrol treatment inhibits acute pharyngitis in the mice model through inhibition of PGE2/COX-2 expression
por: Yu, Zhaoyan, et al.
Publicado: (2018)

NDRG2 Controls COX-2/PGE(2)-Mediated Breast Cancer Cell Migration and Invasion
por: Kim, Myung-Jin, et al.
Publicado: (2014)

6-Shogaol reduces progression of experimental endometriosis in vivo and in vitro via regulation of VGEF and inhibition of COX-2 and PGE2-mediated inflammatory responses
por: Wang, Dan, et al.
Publicado: (2018)

COX-2 Deficiency Promotes White Adipogenesis via PGE2-Mediated Paracrine Mechanism and Exacerbates Diet-Induced Obesity
por: Wang, Chunqing, et al.
Publicado: (2022)

Involvement of TLR4 signaling regulated-COX2/PGE2 axis in liver fibrosis induced by Schistosoma japonicum infection
por: Chen, Lan, et al.
Publicado: (2021)

Norepinephrine enhances the LPS-induced expression of COX-2 and secretion of PGE(2 )in primary rat microglia
por: Schlachetzki, Johannes CM, et al.
Publicado: (2010)

Activation of COX-2/PGE(2) Promotes Sapovirus Replication via the Inhibition of Nitric Oxide Production
por: Alfajaro, Mia Madel, et al.
Publicado: (2017)

Atorvastatin attenuates plaque vulnerability by downregulation of EMMPRIN expression via COX-2/PGE2 pathway
por: Liang, Xing, et al.
Publicado: (2017)

Nitrooleic Acid Protects against Cisplatin Nephropathy: Role of COX-2/mPGES-1/PGE(2) Cascade
por: Wang, Haiping, et al.
Publicado: (2015)

Rheumatoid arthritis synovial fibroblasts promote TREM-1 expression in monocytes via COX-2/PGE(2) pathway
por: Peng, Anping, et al.
Publicado: (2019)

EPC-exosomal miR-26a-5p improves airway remodeling in COPD by inhibiting ferroptosis of bronchial epithelial cells via PTGS2/PGE2 signaling pathway
por: Liu, Caihong, et al.
Publicado: (2023)

Mitochondrial oxidative stress activates COX-2/mPGES-1/PGE2 cascade induced by albumin in renal proximal tubular cells
por: Zhuang, Yibo, et al.
Publicado: (2018)

Inhibition of PI3K-AKT Signaling Blocks PGE(2)-Induced COX-2 Expression in Lung Adenocarcinoma
por: Yang, Jianjian, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_sbj1brmtmf0h8lil9tenk8ivec