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Genetic features and clinical outcomes of patients with isolated and comutated DDX41-mutated myeloid neoplasms

DDX41 mutations (germline and somatic) are associated with late onset myelodysplastic syndromes/acute myeloid leukemia (MDS/AML). Myeloid neoplasms (MN) with germline predisposition was identified as a distinct category in the 2016 WHO classification revision, including MN with germline DDX41 mutati...

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Detalles Bibliográficos
Autores principales: Alkhateeb, Hassan B., Nanaa, Ahmad, Viswanatha, David, Foran, James M., Badar, Talha, Sproat, Lisa, He, Rong, Nguyen, Phuong, Jevremovic, Dragan, Salama, Mohamad E., Greipp, Patricia, Gangat, Naseema, Tefferi, Ayalew, Litzow, Mark R., Mangaonkar, Abhishek A., Shah, Mithun Vinod, Patnaik, Mrinal, Al-Kali, Aref
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791578/
https://www.ncbi.nlm.nih.gov/pubmed/34644397
http://dx.doi.org/10.1182/bloodadvances.2021005738