Tumor-associated antigen–specific T cells with nivolumab are safe and persist in vivo in relapsed/refractory Hodgkin lymphoma

Hodgkin lymphoma (HL) Reed Sternberg cells express tumor-associated antigens (TAA) that are potential targets for cellular therapies. We recently demonstrated that TAA-specific T cells (TAA-Ts) targeting WT1, PRAME, and Survivin were safe and associated with prolonged time to progression in solid tu...

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Detalles Bibliográficos
Autores principales: Dave, Hema, Terpilowski, Madeline, Mai, Mimi, Toner, Keri, Grant, Melanie, Stanojevic, Maja, Lazarski, Christopher, Shibli, Abeer, Bien, Stephanie A., Maglo, Philip, Hoq, Fahmida, Schore, Reuven, Glenn, Martha, Hu, Boyu, Hanley, Patrick J., Ambinder, Richard, Bollard, Catherine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Clinical Trials and Observations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791594/
https://www.ncbi.nlm.nih.gov/pubmed/34495306
http://dx.doi.org/10.1182/bloodadvances.2021005343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791594/
https://www.ncbi.nlm.nih.gov/pubmed/34495306
http://dx.doi.org/10.1182/bloodadvances.2021005343

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