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Deep Learning-Based Chest CT Image Features in Diagnosis of Lung Cancer

This study was to evaluate the diagnostic value of deep learning-optimized chest CT in the patients with lung cancer. 90 patients who were diagnosed with lung cancer by surgery or puncture in hospital were selected as the research subjects. The Mask Region Convolutional Neural Network (Mask-RCNN) mo...

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Detalles Bibliográficos
Autores principales: Feng, Jianxin, Jiang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791752/
https://www.ncbi.nlm.nih.gov/pubmed/35096129
http://dx.doi.org/10.1155/2022/4153211
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author Feng, Jianxin
Jiang, Jun
author_facet Feng, Jianxin
Jiang, Jun
author_sort Feng, Jianxin
collection PubMed
description This study was to evaluate the diagnostic value of deep learning-optimized chest CT in the patients with lung cancer. 90 patients who were diagnosed with lung cancer by surgery or puncture in hospital were selected as the research subjects. The Mask Region Convolutional Neural Network (Mask-RCNN) model was a typical end-to-end image segmentation model, and Dual Path Network (DPN) was used in nodule detection. The results showed that the accuracy of DPN algorithm model in detecting lung lesions in lung cancer patients was 88.74%, the accuracy of CT diagnosis of lung cancer was 88.37%, the sensitivity was 82.91%, and the specificity was 87.43%. Deep learning-based CT examination combined with serum tumor detection, factoring into Neurospecific enolase (N S E), cytokeratin 19 fragment (CYFRA21), Carcinoembryonic antigen (CEA), and squamous cell carcinoma (SCC) antigen, improved the accuracy to 97.94%, the sensitivity to 98.12%, and the specificity to 100%, all showing significant differences (P < 0.05). In conclusion, this study provides a scientific basis for improving the diagnostic efficiency of CT imaging in lung cancer and theoretical support for subsequent lung cancer diagnosis and treatment.
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spelling pubmed-87917522022-01-27 Deep Learning-Based Chest CT Image Features in Diagnosis of Lung Cancer Feng, Jianxin Jiang, Jun Comput Math Methods Med Research Article This study was to evaluate the diagnostic value of deep learning-optimized chest CT in the patients with lung cancer. 90 patients who were diagnosed with lung cancer by surgery or puncture in hospital were selected as the research subjects. The Mask Region Convolutional Neural Network (Mask-RCNN) model was a typical end-to-end image segmentation model, and Dual Path Network (DPN) was used in nodule detection. The results showed that the accuracy of DPN algorithm model in detecting lung lesions in lung cancer patients was 88.74%, the accuracy of CT diagnosis of lung cancer was 88.37%, the sensitivity was 82.91%, and the specificity was 87.43%. Deep learning-based CT examination combined with serum tumor detection, factoring into Neurospecific enolase (N S E), cytokeratin 19 fragment (CYFRA21), Carcinoembryonic antigen (CEA), and squamous cell carcinoma (SCC) antigen, improved the accuracy to 97.94%, the sensitivity to 98.12%, and the specificity to 100%, all showing significant differences (P < 0.05). In conclusion, this study provides a scientific basis for improving the diagnostic efficiency of CT imaging in lung cancer and theoretical support for subsequent lung cancer diagnosis and treatment. Hindawi 2022-01-19 /pmc/articles/PMC8791752/ /pubmed/35096129 http://dx.doi.org/10.1155/2022/4153211 Text en Copyright © 2022 Jianxin Feng and Jun Jiang. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Feng, Jianxin
Jiang, Jun
Deep Learning-Based Chest CT Image Features in Diagnosis of Lung Cancer
title Deep Learning-Based Chest CT Image Features in Diagnosis of Lung Cancer
title_full Deep Learning-Based Chest CT Image Features in Diagnosis of Lung Cancer
title_fullStr Deep Learning-Based Chest CT Image Features in Diagnosis of Lung Cancer
title_full_unstemmed Deep Learning-Based Chest CT Image Features in Diagnosis of Lung Cancer
title_short Deep Learning-Based Chest CT Image Features in Diagnosis of Lung Cancer
title_sort deep learning-based chest ct image features in diagnosis of lung cancer
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791752/
https://www.ncbi.nlm.nih.gov/pubmed/35096129
http://dx.doi.org/10.1155/2022/4153211
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