Clonal and subclonal TP53 molecular impairment is associated with prognosis and progression in multiple myeloma

Aberrations on TP53, either as deletions of chromosome 17p (del17p) or mutations, are associated with poor outcome in multiple myeloma (MM), but conventional detection methods currently in use underestimate their incidence, hindering an optimal risk assessment and prognostication of MM patients. We...

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Detalles Bibliográficos
Autores principales: Martello, M., Poletti, A., Borsi, E., Solli, V., Dozza, L., Barbato, S., Zamagni, E., Tacchetti, P., Pantani, L., Mancuso, K., Vigliotta, I., Rizzello, I., Rocchi, S., Armuzzi, S., Testoni, N., Marzocchi, G., Martinelli, G., Cavo, M., Terragna, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791929/
https://www.ncbi.nlm.nih.gov/pubmed/35082295
http://dx.doi.org/10.1038/s41408-022-00610-y

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