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Modulation of miR-145-5p and miR-146b-5p levels is linked to reduced parasite load in H9C2 Trypanosoma cruzi infected cardiomyoblasts

In the heart tissue of acutely Trypanosoma cruzi-infected mice miR-145-5p and miR-146b-5p are, respectively, downregulated and upregulated. Here, we used the H9C2 rat cardiomyoblast cell line infected with the Colombian T. cruzi strain to investigate the parasite-host cell interplay, focusing on the...

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Detalles Bibliográficos
Autores principales:	Farani, Priscila Silva Grijó, Ferreira, Beatriz Iandra Silva, Gibaldi, Daniel, Lannes-Vieira, Joseli, Moreira, Otacilio Cruz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791985/ https://www.ncbi.nlm.nih.gov/pubmed/35082354 http://dx.doi.org/10.1038/s41598-022-05493-4

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