Cargando…

Immune marker levels in severe mental disorders: associations with polygenic risk scores of related mental phenotypes and psoriasis

Several lines of evidence implicate immune abnormalities in the pathophysiology of severe mental disorders (SMD) and comorbid mental disorders. Here, we use the data from genome-wide association studies (GWAS) of autoimmune diseases and mental phenotypes associated with SMD to disentangle genetic su...

Descripción completa

Detalles Bibliográficos
Autores principales:	Werner, Maren Caroline Frogner, Wirgenes, Katrine Verena, Shadrin, Alexey, Lunding, Synve Hoffart, Rødevand, Linn, Hjell, Gabriela, Ormerod, Monica Bettina Elkjær Greenwood, Haram, Marit, Agartz, Ingrid, Djurovic, Srdjan, Melle, Ingrid, Aukrust, Pål, Ueland, Thor, Andreassen, Ole Andreas, Steen, Nils Eiel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8792001/ https://www.ncbi.nlm.nih.gov/pubmed/35082268 http://dx.doi.org/10.1038/s41398-022-01811-6

Ejemplares similares

Composite immune marker scores associated with severe mental disorders and illness course
por: Elkjaer Greenwood Ormerod, Monica Bettina, et al.
Publicado: (2022)

Expression of ANK3 moderates the association between childhood trauma and affective traits in severe mental disorders
por: Aas, Monica, et al.
Publicado: (2023)

Childhood trauma and cardiometabolic risk in severe mental disorders: The mediating role of cognitive control
por: Lunding, Synve Hoffart, et al.
Publicado: (2021)

Impulsivity across severe mental disorders: a cross-sectional study of immune markers and psychopharmacotherapy
por: Hjell, Gabriela, et al.
Publicado: (2023)

Disentangling the relationship between cholesterol, aggression, and impulsivity in severe mental disorders
por: Hjell, Gabriela, et al.
Publicado: (2020)

Inflammation and cognition in severe mental illness: patterns of covariation and subgroups
por: Sæther, Linn Sofie, et al.
Publicado: (2022)

Affective lability and social functioning in severe mental disorders
por: Høegh, Margrethe Collier, et al.
Publicado: (2022)

S96. CARDIOVASCULAR DISEASE RISK IN PATIENTS WITH SCHIZOPHRENIA AND BIPOLAR DISORDER
por: Rødevand, Linn, et al.
Publicado: (2018)

Adiponectin Is Related to Cardiovascular Risk in Severe Mental Illness Independent of Antipsychotic Treatment
por: Reponen, Elina J., et al.
Publicado: (2021)

Distinct multivariate brain morphological patterns and their added predictive value with cognitive and polygenic risk scores in mental disorders
por: Doan, Nhat Trung, et al.
Publicado: (2017)

Telomere length is associated with childhood trauma in patients with severe mental disorders
por: Aas, Monica, et al.
Publicado: (2019)

Sleep disturbance mediates the link between childhood trauma and clinical outcome in severe mental disorders
por: Laskemoen, Jannicke Fjæra, et al.
Publicado: (2021)

Childhood Trauma Is Nominally Associated With Elevated Cortisol Metabolism in Severe Mental Disorder
por: Aas, Monica, et al.
Publicado: (2020)

Altered Brain Activation during Emotional Face Processing in Relation to Both Diagnosis and Polygenic Risk of Bipolar Disorder
por: Tesli, Martin, et al.
Publicado: (2015)

Polygenic overlap and shared genetic loci between loneliness, severe mental disorders, and cardiovascular disease risk factors suggest shared molecular mechanisms
por: Rødevand, Linn, et al.
Publicado: (2021)

Association between Genetic Variation in the Oxytocin Receptor Gene and Emotional Withdrawal, but not between Oxytocin Pathway Genes and Diagnosis in Psychotic Disorders
por: Haram, Marit, et al.
Publicado: (2015)

Oxytocin-pathway polygenic scores for severe mental disorders and metabolic phenotypes in the UK Biobank
por: Winterton, Adriano, et al.
Publicado: (2021)

Attenuated Notch signaling in schizophrenia and bipolar disorder
por: Hoseth, Eva Z., et al.
Publicado: (2018)

Exploring the Wnt signaling pathway in schizophrenia and bipolar disorder
por: Hoseth, Eva Z., et al.
Publicado: (2018)

Polygenic scores for schizophrenia and general cognitive ability: associations with six cognitive domains, premorbid intelligence, and cognitive composite score in individuals with a psychotic disorder and in healthy controls
por: Engen, Magnus Johan, et al.
Publicado: (2020)

Neurocognitive Decrements are Present in Intellectually Superior Schizophrenia
por: Vaskinn, Anja, et al.
Publicado: (2014)

Lower circulating neuron-specific enolase concentrations in adults and adolescents with severe mental illness
por: Andreou, Dimitrios, et al.
Publicado: (2023)

Cannabis Use Is Associated With Increased Levels of Soluble gp130 in Schizophrenia but Not in Bipolar Disorder
por: Szabo, Attila, et al.
Publicado: (2020)

CACNA1C Risk Variant and Amygdala Activity in Bipolar Disorder, Schizophrenia and Healthy Controls
por: Tesli, Martin, et al.
Publicado: (2013)

Correction: CACNA1C Risk Variant and Amygdala Activity in Bipolar Disorder, Schizophrenia and Healthy Controls
por: Tesli, Martin, et al.
Publicado: (2013)

Atherogenic Lipid Ratios Related to Myeloperoxidase and C-Reactive Protein Levels in Psychotic Disorders
por: Reponen, Elina J., et al.
Publicado: (2020)

Characterising the shared genetic determinants of bipolar disorder, schizophrenia and risk-taking
por: Hindley, Guy, et al.
Publicado: (2021)

Contribution of oxytocin receptor polymorphisms to amygdala activation in schizophrenia spectrum disorders
por: Haram, Marit, et al.
Publicado: (2016)

Association between a genetic variant in the serotonin transporter gene (SLC6A4) and suicidal behavior in patients with schizophrenia
por: Lindholm Carlström, Eva, et al.
Publicado: (2012)

Attitudes among parents of persons with autism spectrum disorder towards information about genetic risk and future health
por: Johannessen, Jarle, et al.
Publicado: (2021)

Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools
por: Bahrami, Shahram, et al.
Publicado: (2021)

The estrogen hypothesis of Schizophrenia implicates glucose metabolism: Association study in three independent samples
por: Olsen, Line, et al.
Publicado: (2008)

Extensive bidirectional genetic overlap between bipolar disorder and cardiovascular disease phenotypes
por: Rødevand, Linn, et al.
Publicado: (2021)

Herpes simplex virus 1 infection on grey matter and general intelligence in severe mental illness
por: Andreou, Dimitrios, et al.
Publicado: (2022)

Brain Expressed microRNAs Implicated in Schizophrenia Etiology
por: Hansen, Thomas, et al.
Publicado: (2007)

T229. ANTIPSYCHOTIC DRUG USE AND THYROID FUNCTION IN PATIENTS WITH SEVERE MENTAL DISORDERS
por: Iversen, Trude, et al.
Publicado: (2018)

Microarray Analysis of Copy Number Variants on the Human Y Chromosome Reveals Novel and Frequent Duplications Overrepresented in Specific Haplogroups
por: Johansson, Martin M., et al.
Publicado: (2015)

Bivariate causal mixture model quantifies polygenic overlap between complex traits beyond genetic correlation
por: Frei, Oleksandr, et al.
Publicado: (2019)

Serum concentrations of mood stabilizers are associated with memory, but not other cognitive domains in psychosis spectrum disorders; explorative analyses in a naturalistic setting
por: Steen, Nils Eiel, et al.
Publicado: (2016)

Patients with schizophrenia and bipolar disorder display a similar global gene expression signature in whole blood that reflects elevated proportion of immature neutrophil cells with association to lipid changes
por: Torsvik, Anja, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_e6pga85ao7rt7q7v7nodn7qp5c