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Low CCR5 expression protects HIV-specific CD4+ T cells of elite controllers from viral entry

HIV elite controllers maintain a population of CD4 + T cells endowed with high avidity for Gag antigens and potent effector functions. How these HIV-specific cells avoid infection and depletion upon encounter with the virus remains incompletely understood. Ex vivo characterization of single Gag-spec...

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Detalles Bibliográficos
Autores principales:	Claireaux, Mathieu, Robinot, Rémy, Kervevan, Jérôme, Patgaonkar, Mandar, Staropoli, Isabelle, Brelot, Anne, Nouël, Alexandre, Gellenoncourt, Stacy, Tang, Xian, Héry, Mélanie, Volant, Stevenn, Perthame, Emeline, Avettand-Fenoël, Véronique, Buchrieser, Julian, Cokelaer, Thomas, Bouchier, Christiane, Ma, Laurence, Boufassa, Faroudy, Hendou, Samia, Libri, Valentina, Hasan, Milena, Zucman, David, de Truchis, Pierre, Schwartz, Olivier, Lambotte, Olivier, Chakrabarti, Lisa A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8792008/ https://www.ncbi.nlm.nih.gov/pubmed/35082297 http://dx.doi.org/10.1038/s41467-022-28130-0

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