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Defective humoral immunity disrupts bile acid homeostasis which promotes inflammatory disease of the small bowel

Mucosal antibodies maintain gut homeostasis by promoting spatial segregation between host tissues and luminal microbes. Whether and how mucosal antibody responses influence gut health through modulation of microbiota composition is unclear. Here, we use a CD19(−/−) mouse model of antibody-deficiency...

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Detalles Bibliográficos
Autores principales:	Mohammed, Ahmed Dawood, Mohammed, Zahraa, Roland, Mary M., Chatzistamou, Ioulia, Jolly, Amy, Schoettmer, Lillian M., Arroyo, Mireya, Kakar, Khadija, Tian, Yuan, Patterson, Andrew, Nagarkatti, Mitzi, Nagarkatti, Prakash, Kubinak, Jason L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8792037/ https://www.ncbi.nlm.nih.gov/pubmed/35082296 http://dx.doi.org/10.1038/s41467-022-28126-w

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