Mendelian randomization study on the causal effects of tumor necrosis factor inhibition on coronary artery disease and ischemic stroke among the general population

BACKGROUND: Tumor necrosis factor (TNF) is a potent inflammatory cytokine that has been causally associated with coronary artery disease (CAD) and ischemic stroke (IS), implying opportunities for disease prevention by anti-TNF therapeutics. METHODS: Leveraging summary statistics of several genome-wi...

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Detalles Bibliográficos
Autores principales: Kang, Xiaoying, Jiao, Tong, Wang, Haiyang, Pernow, John, Wirdefeldt, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8792065/
https://www.ncbi.nlm.nih.gov/pubmed/35074627
http://dx.doi.org/10.1016/j.ebiom.2022.103824

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