Multi-omics analysis identifies essential regulators of mitochondrial stress response in two wild-type C. elegans strains

The mitochondrial unfolded protein response (UPRmt) is a promising pharmacological target for aging and age-related diseases. However, the integrative analysis of the impact of UPRmt activation on different signaling layers in animals with different genetic backgrounds is lacking. Here, we applied s...

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Detalles Bibliográficos
Autores principales: Gao, Arwen W., El Alam, Gaby, Lalou, Amélia, Li, Terytty Yang, Molenaars, Marte, Zhu, Yunyun, Overmyer, Katherine A., Shishkova, Evgenia, Hof, Kevin, Bou Sleiman, Maroun, Houtkooper, Riekelt H., Coon, Joshua J., Auwerx, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8792074/
https://www.ncbi.nlm.nih.gov/pubmed/35118355
http://dx.doi.org/10.1016/j.isci.2022.103734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8792074/
https://www.ncbi.nlm.nih.gov/pubmed/35118355
http://dx.doi.org/10.1016/j.isci.2022.103734

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