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Tumor-Specific Major Histocompatibility-II Expression Predicts Benefit to Anti–PD-1/L1 Therapy in Patients With HER2-Negative Primary Breast Cancer
PURPOSE: Immunotherapies targeting PD-1/L1 enhance pathologic complete response (pCR) rates when added to standard neoadjuvant chemotherapy (NAC) regimens in early-stage triple-negative, and possibly high-risk estrogen receptor–positive breast cancer. However, immunotherapy has been associated with...
Autores principales: | Gonzalez-Ericsson, Paula I., Wulfkhule, Julia D., Gallagher, Rosa I., Sun, Xiaopeng, Axelrod, Margaret L., Sheng, Quanhu, Luo, Na, Gomez, Henry, Sanchez, Violeta, Sanders, Melinda, Pusztai, Lajos, Petricoin, Emanuel, Blenman, Kim R.M., Balko, Justin M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8792110/ https://www.ncbi.nlm.nih.gov/pubmed/34315723 http://dx.doi.org/10.1158/1078-0432.CCR-21-0607 |
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