An Electrochemical Way to Generate Amphiphiles from Hydrazones for the Synthesis of 1,2,4‐Triazole Scaffold Cyclic Compounds

An electro‐oxidative cyclization pathway in which hydrazones are selected as starting materials to generate amphiphiles by reacting with benzylamines and benzamides was reported. This strategy successfully prepared a series of 1,2,4‐triazoles in satisfactory yields. Moreover, the use of cheap stainl...

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Autores principales: Li, Wangyu, Xiong, Mingteng, Liang, Xiao, Wang, Dungai, Zhu, Heping, Pan, Yuanjiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8792120/
https://www.ncbi.nlm.nih.gov/pubmed/35083886
http://dx.doi.org/10.1002/open.202100268
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author Li, Wangyu
Xiong, Mingteng
Liang, Xiao
Wang, Dungai
Zhu, Heping
Pan, Yuanjiang
author_facet Li, Wangyu
Xiong, Mingteng
Liang, Xiao
Wang, Dungai
Zhu, Heping
Pan, Yuanjiang
author_sort Li, Wangyu
collection PubMed
description An electro‐oxidative cyclization pathway in which hydrazones are selected as starting materials to generate amphiphiles by reacting with benzylamines and benzamides was reported. This strategy successfully prepared a series of 1,2,4‐triazoles in satisfactory yields. Moreover, the use of cheap stainless steel as the anode, the feasibility to conduct the transformation as a one‐pot reaction and the proof that scaling‐up these reactions is possible make this transformation attractive for potential application in industry.
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spelling pubmed-87921202022-02-04 An Electrochemical Way to Generate Amphiphiles from Hydrazones for the Synthesis of 1,2,4‐Triazole Scaffold Cyclic Compounds Li, Wangyu Xiong, Mingteng Liang, Xiao Wang, Dungai Zhu, Heping Pan, Yuanjiang ChemistryOpen Research Articles An electro‐oxidative cyclization pathway in which hydrazones are selected as starting materials to generate amphiphiles by reacting with benzylamines and benzamides was reported. This strategy successfully prepared a series of 1,2,4‐triazoles in satisfactory yields. Moreover, the use of cheap stainless steel as the anode, the feasibility to conduct the transformation as a one‐pot reaction and the proof that scaling‐up these reactions is possible make this transformation attractive for potential application in industry. John Wiley and Sons Inc. 2022-01-26 /pmc/articles/PMC8792120/ /pubmed/35083886 http://dx.doi.org/10.1002/open.202100268 Text en © 2022 The Authors. Published by Wiley-VCH GmbH https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Research Articles
Li, Wangyu
Xiong, Mingteng
Liang, Xiao
Wang, Dungai
Zhu, Heping
Pan, Yuanjiang
An Electrochemical Way to Generate Amphiphiles from Hydrazones for the Synthesis of 1,2,4‐Triazole Scaffold Cyclic Compounds
title An Electrochemical Way to Generate Amphiphiles from Hydrazones for the Synthesis of 1,2,4‐Triazole Scaffold Cyclic Compounds
title_full An Electrochemical Way to Generate Amphiphiles from Hydrazones for the Synthesis of 1,2,4‐Triazole Scaffold Cyclic Compounds
title_fullStr An Electrochemical Way to Generate Amphiphiles from Hydrazones for the Synthesis of 1,2,4‐Triazole Scaffold Cyclic Compounds
title_full_unstemmed An Electrochemical Way to Generate Amphiphiles from Hydrazones for the Synthesis of 1,2,4‐Triazole Scaffold Cyclic Compounds
title_short An Electrochemical Way to Generate Amphiphiles from Hydrazones for the Synthesis of 1,2,4‐Triazole Scaffold Cyclic Compounds
title_sort electrochemical way to generate amphiphiles from hydrazones for the synthesis of 1,2,4‐triazole scaffold cyclic compounds
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8792120/
https://www.ncbi.nlm.nih.gov/pubmed/35083886
http://dx.doi.org/10.1002/open.202100268
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