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A protocol to extract cell-type-specific signatures from differentially expressed genes in bulk-tissue RNA-seq
Bulk-tissue RNA-seq is widely used to dissect variation in gene expression levels across tissues and under different experimental conditions. Here, we introduce a protocol that leverages existing single-cell expression data to deconvolve patterns of cell-type-specific gene expression in differential...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8792262/ https://www.ncbi.nlm.nih.gov/pubmed/35118429 http://dx.doi.org/10.1016/j.xpro.2022.101121 |