A protocol to extract cell-type-specific signatures from differentially expressed genes in bulk-tissue RNA-seq

Bulk-tissue RNA-seq is widely used to dissect variation in gene expression levels across tissues and under different experimental conditions. Here, we introduce a protocol that leverages existing single-cell expression data to deconvolve patterns of cell-type-specific gene expression in differential...

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Detalles Bibliográficos
Autores principales: Marquez-Galera, Angel, de la Prida, Liset M., Lopez-Atalaya, Jose P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8792262/
https://www.ncbi.nlm.nih.gov/pubmed/35118429
http://dx.doi.org/10.1016/j.xpro.2022.101121

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