Cargando…

Molecular Characterization and Clinical Relevance of ALDH2 in Human Cancers

Background: Aldehyde dehydrogenase 2 (ALDH2) is well-known to be a key enzyme in alcohol metabolism. However, a comprehensive understanding of ALDH2 across human cancers is lacking. Methods: A systematic and comprehensive analysis of the molecular alterations and clinical relevance for ALDH2 in more...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ma, Bo, Liu, Zaoqu, Xu, Hui, Liu, Long, Huang, Tao, Meng, Lingfang, Wang, Libo, Zhang, Yuyuan, Li, Lifeng, Han, Xinwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8792945/ https://www.ncbi.nlm.nih.gov/pubmed/35096916 http://dx.doi.org/10.3389/fmed.2021.832605

Ejemplares similares

Comprehensive Molecular Analyses of a Six-Gene Signature for Predicting Late Recurrence of Hepatocellular Carcinoma
por: Zhang, Yuyuan, et al.
Publicado: (2021)

Comprehensive Molecular Analyses of a Novel Mutational Signature Classification System with Regard to Prognosis, Genomic Alterations, and Immune Landscape in Glioma
por: Liu, Zaoqu, et al.
Publicado: (2021)

Epigenetically regulated gene expression profiles decipher four molecular subtypes with prognostic and therapeutic implications in gastric cancer
por: Weng, Siyuan, et al.
Publicado: (2023)

Hypoxia Molecular Characterization in Hepatocellular Carcinoma Identifies One Risk Signature and Two Nomograms for Clinical Management
por: Liu, Zaoqu, et al.
Publicado: (2021)

Clinical Application Value of Circulating Cell-free DNA in Hepatocellular Carcinoma
por: Zhang, Yuyuan, et al.
Publicado: (2021)

Epigenetic Signaling of Cancer Stem Cells During Inflammation
por: Liu, Zaoqu, et al.
Publicado: (2021)

Implications of pseudogenes for the prognosis of hepatocellular carcinoma
por: Liu, Zaoqu, et al.
Publicado: (2023)

Editorial: Application of artificial intelligence in improving immunotherapeutic efficacy
por: Li, Jie, et al.
Publicado: (2022)

Gene expression profiles contribute to robustly predicting prognosis in hepatocellular carcinoma
por: Liu, Long, et al.
Publicado: (2023)

Machine learning-based integration develops an immune-derived lncRNA signature for improving outcomes in colorectal cancer
por: Liu, Zaoqu, et al.
Publicado: (2022)

Computational Recognition and Clinical Verification of TGF-β-Derived miRNA Signature With Potential Implications in Prognosis and Immunotherapy of Intrahepatic Cholangiocarcinoma
por: Liu, Zaoqu, et al.
Publicado: (2021)

EGR1 and KLF4 as Diagnostic Markers for Abdominal Aortic Aneurysm and Associated With Immune Infiltration
por: Guo, Chunguang, et al.
Publicado: (2022)

CELF2 is a candidate prognostic and immunotherapy biomarker in triple‐negative breast cancer and lung squamous cell carcinoma: A pan‐cancer analysis
por: Wang, Libo, et al.
Publicado: (2021)

Genomic Alteration Characterization in Colorectal Cancer Identifies a Prognostic and Metastasis Biomarker: FAM83A|IDO1
por: Liu, Zaoqu, et al.
Publicado: (2021)

Derivation and Clinical Validation of a Redox-Driven Prognostic Signature for Colorectal Cancer
por: Dang, Qin, et al.
Publicado: (2021)

Multi-omics landscape and clinical significance of a SMAD4-driven immune signature: Implications for risk stratification and frontline therapies in pancreatic cancer
por: Wang, Libo, et al.
Publicado: (2022)

An Integrated Fibrosis Signature for Predicting Survival and Immunotherapy Efficacy of Patients With Hepatocellular Carcinoma
por: Liu, Long, et al.
Publicado: (2021)

Somatic mutations in homologous recombination pathway predict favourable prognosis after immunotherapy across multiple cancer types
por: Liu, Zaoqu, et al.
Publicado: (2021)

The Identification and Validation of Two Heterogenous Subtypes and a Risk Signature Based on Ferroptosis in Hepatocellular Carcinoma
por: Liu, Zaoqu, et al.
Publicado: (2021)

Exploring the roles of intestinal flora in enhanced recovery after surgery
por: Liu, Zaoqu, et al.
Publicado: (2023)

Biological and pharmacological roles of m(6)A modifications in cancer drug resistance
por: Liu, Zaoqu, et al.
Publicado: (2022)

Editorial: Using multi-omics to develop new strategies to improve prognosis and immunotherapy outcomes in cancers
por: Cao, Chenxi, et al.
Publicado: (2023)

A New Trend in Cancer Treatment: The Combination of Epigenetics and Immunotherapy
por: Liu, Zaoqu, et al.
Publicado: (2022)

Immunosenescence: molecular mechanisms and diseases
por: Liu, Zaoqu, et al.
Publicado: (2023)

Integrative bioinformatics analysis to explore a robust diagnostic signature and landscape of immune cell infiltration in sarcoidosis
por: Duo, Mengjie, et al.
Publicado: (2022)

ALDH Expression in Angiosarcoma of the Lung: A Potential Marker of Aggressiveness?
por: Aramini, Beatrice, et al.
Publicado: (2020)

Integrative pharmacogenomics revealed three subtypes with different immune landscapes and specific therapeutic responses in lung adenocarcinoma
por: Ge, Xiaoyong, et al.
Publicado: (2022)

Construction of a diagnostic signature and immune landscape of pulmonary arterial hypertension
por: Duo, Mengjie, et al.
Publicado: (2022)

Ferroptosis: a double-edged sword mediating immune tolerance of cancer
por: Dang, Qin, et al.
Publicado: (2022)

Exploring Key Genes to Construct a Diagnosis Model of Dilated Cardiomyopathy
por: Zheng, Youyang, et al.
Publicado: (2022)

A novel immune classification reveals distinct immune escape mechanism and genomic alterations: implications for immunotherapy in hepatocellular carcinoma
por: Liu, Zaoqu, et al.
Publicado: (2021)

Antitumor effects of fecal microbiota transplantation: Implications for microbiome modulation in cancer treatment
por: Xu, Hui, et al.
Publicado: (2022)

Epigenetically regulated gene expression profiles recognized three molecular classifications with prognostic and therapeutic implications in bladder cancer
por: Xu, Hui, et al.
Publicado: (2023)

TTN/OBSCN ‘Double‐Hit’ predicts favourable prognosis, ‘immune‐hot’ subtype and potentially better immunotherapeutic efficacy in colorectal cancer
por: Liu, Zaoqu, et al.
Publicado: (2021)

Association of RYR2 Mutation With Tumor Mutation Burden, Prognosis, and Antitumor Immunity in Patients With Esophageal Adenocarcinoma
por: Liu, Zaoqu, et al.
Publicado: (2021)

Genetic Variations of ALDH (rs671) Are Associated With the Persistence of HBV Infection Among the Chinese Han Population
por: Shang, Dabao, et al.
Publicado: (2022)

Integrative analysis from multi-center studies identities a consensus machine learning-derived lncRNA signature for stage II/III colorectal cancer
por: Liu, Zaoqu, et al.
Publicado: (2021)

SCG2: A Prognostic Marker That Pinpoints Chemotherapy and Immunotherapy in Colorectal Cancer
por: Weng, Siyuan, et al.
Publicado: (2022)

Expression of ALDH and SOX-2 in Pulmonary Sclerosing Pnemocytoma (PSP) of the Lung: Is There a Meaning Behind?
por: Aramini, Beatrice, et al.
Publicado: (2020)

The Role of Acsl1 and Aldh2 in the Increased Risk for Liver Cancer in Offspring of Obese Mothers
por: Moeckli, Beat, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_7gbgeg9akjnu4e3r553a4de5e8