Structural Insights for Core Scaffold and Substrate Specificity of B1, B2, and B3 Metallo-β-Lactamases

Metallo-β-lactamases (MBLs) hydrolyze almost all β-lactam antibiotics, including penicillins, cephalosporins, and carbapenems; however, no effective inhibitors are currently clinically available. MBLs are classified into three subclasses: B1, B2, and B3. Although the amino acid sequences of MBLs are...

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Detalles Bibliográficos
Autores principales: Yun, Yeongjin, Han, Sangjun, Park, Yoon Sik, Park, Hyunjae, Kim, Dogyeong, Kim, Yeseul, Kwon, Yongdae, Kim, Sumin, Lee, Jung Hun, Jeon, Jeong Ho, Lee, Sang Hee, Kang, Lin-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8792953/
https://www.ncbi.nlm.nih.gov/pubmed/35095785
http://dx.doi.org/10.3389/fmicb.2021.752535

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8792953/
https://www.ncbi.nlm.nih.gov/pubmed/35095785
http://dx.doi.org/10.3389/fmicb.2021.752535

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