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Detecting Differences in Prion Protein Conformation by Quantifying Methionine Oxidation
[Image: see text] A prion’s pathogenic character is enciphered in its conformation, which also defines the chemical environments of its amino acids. Differences in chemical environments influence the reactivity of amino acid side chains, in a conformation-dependent manner. Chemical oxidation of susc...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793083/ https://www.ncbi.nlm.nih.gov/pubmed/35097263 http://dx.doi.org/10.1021/acsomega.1c04989 |