Mutational landscape of circulating tumor DNA identifies distinct molecular features associated with therapeutic response in patients with metastatic colorectal cancer

BACKGROUND: We investigated the mutational landscape of circulating tumor DNA (ctDNA) in predicting tumor response to first-line treatment in patients with metastatic colorectal cancer (mCRC). METHODS: We included 41 patients with initially unresectable mCRC, treated with 5-fluorouracil/leucovorin/o...

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Detalles Bibliográficos
Autores principales: Shi, Min, Yuan, Hong, Ji, Jun, Zhang, Shouwei, Li, Qingyuan, Chen, Yawei, Gong, Xiaoli, Zhu, Zhenggang, Zhang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793119/
https://www.ncbi.nlm.nih.gov/pubmed/35096147
http://dx.doi.org/10.1177/17588359211070643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793119/
https://www.ncbi.nlm.nih.gov/pubmed/35096147
http://dx.doi.org/10.1177/17588359211070643

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