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Mutational landscape of circulating tumor DNA identifies distinct molecular features associated with therapeutic response in patients with metastatic colorectal cancer

BACKGROUND: We investigated the mutational landscape of circulating tumor DNA (ctDNA) in predicting tumor response to first-line treatment in patients with metastatic colorectal cancer (mCRC). METHODS: We included 41 patients with initially unresectable mCRC, treated with 5-fluorouracil/leucovorin/o...

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Detalles Bibliográficos
Autores principales:	Shi, Min, Yuan, Hong, Ji, Jun, Zhang, Shouwei, Li, Qingyuan, Chen, Yawei, Gong, Xiaoli, Zhu, Zhenggang, Zhang, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793119/ https://www.ncbi.nlm.nih.gov/pubmed/35096147 http://dx.doi.org/10.1177/17588359211070643

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