Identification of a novel HOOK3-FGFR1 fusion gene involved in activation of the NF-kappaB pathway

BACKGROUND: Rearrangements involving the fibroblast growth factor receptor 1 (FGFR1) gene result in 8p11 myeloproliferative syndrome (EMS), which is a rare and aggressive hematological malignancy that is often initially diagnosed as myelodysplastic syndrome (MDS). Clinical outcomes are typically poo...

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Detalles Bibliográficos
Autores principales: Zhang, Xuehong, Wang, Furong, Yan, Fanzhi, Huang, Dan, Wang, Haina, Gao, Beibei, Gao, Yuan, Hou, Zhijie, Lou, Jiacheng, Li, Weiling, Yan, Jinsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793161/
https://www.ncbi.nlm.nih.gov/pubmed/35081975
http://dx.doi.org/10.1186/s12935-022-02451-y

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