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Ononin ameliorates inflammation and cartilage degradation in rat chondrocytes with IL-1β-induced osteoarthritis by downregulating the MAPK and NF-κB pathways

BACKGROUND: Osteoarthritis (OA) treatment aims to improve inflammation and delay cartilage degeneration. However, there is no effective strategy presently available. Ononin, a representative isoflavone glycoside component extracted from natural Chinese herbs, exerts anti-inflammatory and proliferati...

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Detalles Bibliográficos
Autores principales:	Xu, Fang, Zhao, Liang-Jun, Liao, Ting, Li, Zhao-Cong, Wang, Lei-Lei, Lin, Pan-Yu, Jiang, Rui, Wei, Qing-Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793192/ https://www.ncbi.nlm.nih.gov/pubmed/35086536 http://dx.doi.org/10.1186/s12906-022-03504-5

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