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Bone marrow stromal antigen 2 (BST-2) genetic variants influence expression levels and disease outcome in HIV-1 chronically infected patients

BACKGROUND: Bone marrow stromal antigen 2 (BST-2) also known as Tetherin (CD317/HM1.24), is a host restriction factor that blocks the release of HIV-1 virions from infected cells. Previous studies reported that BST-2 genetic variants or single nucleotide polymorphims (SNPs) have a preventative role...

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Detalles Bibliográficos
Autores principales:	Mlimi, Hlelolwenkosi, Naidoo, Kewreshini K., Mabuka, Jenniffer, Ndung’u, Thumbi, Madlala, Paradise
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793201/ https://www.ncbi.nlm.nih.gov/pubmed/35081977 http://dx.doi.org/10.1186/s12977-022-00588-2

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