Reactive oxygen species reprogram macrophages to suppress antitumor immune response through the exosomal miR-155-5p/PD-L1 pathway

BACKGROUND: Cancer cells have an imbalance in oxidation-reduction (redox) homeostasis. Understanding the precise mechanisms and the impact of the altered redox microenvironment on the immunologic reaction to tumors is limited. METHODS: We isolated exosomes from ovarian cancer cells through ultracent...

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Detalles Bibliográficos
Autores principales: Li, Xiang, Wang, Shaomin, Mu, Wei, Barry, Jennifer, Han, Anna, Carpenter, Richard L., Jiang, Bing-Hua, Peiper, Stephen C., Mahoney, Mỹ G., Aplin, Andrew E., Ren, Hong, He, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793215/
https://www.ncbi.nlm.nih.gov/pubmed/35086548
http://dx.doi.org/10.1186/s13046-022-02244-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793215/
https://www.ncbi.nlm.nih.gov/pubmed/35086548
http://dx.doi.org/10.1186/s13046-022-02244-1

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