Resveratrol ameliorates myocardial fibrosis by regulating Sirt1/Smad3 deacetylation pathway in rat model with dilated cardiomyopathy

BACKGROUND: The aim of this study was to investigate the effects of Resveratrol (RSV) in rats with dilated cardiomyopathy (DCM). METHODS: Porcine cardiac myosin was used to set up rat model with DCM. RSV (10 mg/kg in RSV-L group and 50 mg/kg in RSV-H group) or vehicle was administered to rats with D...

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Detalles Bibliográficos
Autores principales: Chen, Qingquan, Zeng, Yu, Yang, Xiulin, Wu, Yue, Zhang, Shuyu, Huang, Shirong, Zhong, Yameng, Chen, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793224/
https://www.ncbi.nlm.nih.gov/pubmed/35081907
http://dx.doi.org/10.1186/s12872-021-02401-y

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