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Apolipoprotein (a)/Lipoprotein(a)-Induced Oxidative-Inflammatory α7-nAChR/p38 MAPK/IL-6/RhoA-GTP Signaling Axis and M1 Macrophage Polarization Modulate Inflammation-Associated Development of Coronary Artery Spasm

OBJECTIVE: Apolipoprotein (a)/lipoprotein(a) (Lp(a)), a major carrier of oxidized phospholipids, and α7-nicotinic acetylcholine receptor (α7-nAChR) may play an important role in the development of coronary artery spasm (CAS). In CAS, the association between Lp(a) and the α7-nAChR-modulated inflammat...

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Detalles Bibliográficos
Autores principales:	Lin, Yen-Kuang, Yeh, Chi-Tai, Kuo, Kuang-Tai, Fong, Iat-Hang, Yadav, Vijesh Kumar, Kounis, Nicholas G., Hu, Patrick, Hung, Ming-Yow
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793348/ https://www.ncbi.nlm.nih.gov/pubmed/35096275 http://dx.doi.org/10.1155/2022/9964689

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