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COVID-19 in Pediatrics: Demographic, Clinical, Laboratory, and Radiological Characteristics of Infected Patients With SARS-CoV-2
The COVID-19 disease usually leads to mild infectious disease in children, but some develop serious complications. Here, we describe the characteristics of children with COVID-19 in northern Iran, the Golestan province. Ninety-one confirmed cases were enrolled in the study, aged 0–18 years. Demograp...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793734/ https://www.ncbi.nlm.nih.gov/pubmed/35096716 http://dx.doi.org/10.3389/fped.2021.808187 |
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author | Najafinejad, Maryam Cheraghali, Fatemeh Aghcheli, Bahman Rajabi, Abdolhalim Barati, Leila Naziri, Hamed Gharib, Mohammad Hadi Tabarraei, Alijan Nakstad, Britt Tahamtan, Alireza |
author_facet | Najafinejad, Maryam Cheraghali, Fatemeh Aghcheli, Bahman Rajabi, Abdolhalim Barati, Leila Naziri, Hamed Gharib, Mohammad Hadi Tabarraei, Alijan Nakstad, Britt Tahamtan, Alireza |
author_sort | Najafinejad, Maryam |
collection | PubMed |
description | The COVID-19 disease usually leads to mild infectious disease in children, but some develop serious complications. Here, we describe the characteristics of children with COVID-19 in northern Iran, the Golestan province. Ninety-one confirmed cases were enrolled in the study, aged 0–18 years. Demographic, clinical, comorbidity, laboratory, and radiological data were compared based on the disease severity (admitted to intensive care unit (ICU) or not) and disease outcome (recovered or deceased). Sixteen (17.5%) cases were hospitalized in ICU, and 8/91 (8.8%) deceased. Fever and cough were the most common clinical symptoms. Among all symptoms notified there were no significant differences between severe and milder cases, or between those who deceased and recovered. Failure to thrive (FTT), malignant disease and neurological disease were significantly more prevalent in severe cases as was frequently reported comorbidities. Laterality, ground-glass opacity, and lung consolidation were the most common findings in chest computed tomography. The data confirms that the COVID-19 disease has various presentations in children, and clinical, laboratory, and radiological findings may help predict the development of severe forms of COVID-19 among children. |
format | Online Article Text |
id | pubmed-8793734 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-87937342022-01-28 COVID-19 in Pediatrics: Demographic, Clinical, Laboratory, and Radiological Characteristics of Infected Patients With SARS-CoV-2 Najafinejad, Maryam Cheraghali, Fatemeh Aghcheli, Bahman Rajabi, Abdolhalim Barati, Leila Naziri, Hamed Gharib, Mohammad Hadi Tabarraei, Alijan Nakstad, Britt Tahamtan, Alireza Front Pediatr Pediatrics The COVID-19 disease usually leads to mild infectious disease in children, but some develop serious complications. Here, we describe the characteristics of children with COVID-19 in northern Iran, the Golestan province. Ninety-one confirmed cases were enrolled in the study, aged 0–18 years. Demographic, clinical, comorbidity, laboratory, and radiological data were compared based on the disease severity (admitted to intensive care unit (ICU) or not) and disease outcome (recovered or deceased). Sixteen (17.5%) cases were hospitalized in ICU, and 8/91 (8.8%) deceased. Fever and cough were the most common clinical symptoms. Among all symptoms notified there were no significant differences between severe and milder cases, or between those who deceased and recovered. Failure to thrive (FTT), malignant disease and neurological disease were significantly more prevalent in severe cases as was frequently reported comorbidities. Laterality, ground-glass opacity, and lung consolidation were the most common findings in chest computed tomography. The data confirms that the COVID-19 disease has various presentations in children, and clinical, laboratory, and radiological findings may help predict the development of severe forms of COVID-19 among children. Frontiers Media S.A. 2022-01-13 /pmc/articles/PMC8793734/ /pubmed/35096716 http://dx.doi.org/10.3389/fped.2021.808187 Text en Copyright © 2022 Najafinejad, Cheraghali, Aghcheli, Rajabi, Barati, Naziri, Gharib, Tabarraei, Nakstad and Tahamtan. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Pediatrics Najafinejad, Maryam Cheraghali, Fatemeh Aghcheli, Bahman Rajabi, Abdolhalim Barati, Leila Naziri, Hamed Gharib, Mohammad Hadi Tabarraei, Alijan Nakstad, Britt Tahamtan, Alireza COVID-19 in Pediatrics: Demographic, Clinical, Laboratory, and Radiological Characteristics of Infected Patients With SARS-CoV-2 |
title | COVID-19 in Pediatrics: Demographic, Clinical, Laboratory, and Radiological Characteristics of Infected Patients With SARS-CoV-2 |
title_full | COVID-19 in Pediatrics: Demographic, Clinical, Laboratory, and Radiological Characteristics of Infected Patients With SARS-CoV-2 |
title_fullStr | COVID-19 in Pediatrics: Demographic, Clinical, Laboratory, and Radiological Characteristics of Infected Patients With SARS-CoV-2 |
title_full_unstemmed | COVID-19 in Pediatrics: Demographic, Clinical, Laboratory, and Radiological Characteristics of Infected Patients With SARS-CoV-2 |
title_short | COVID-19 in Pediatrics: Demographic, Clinical, Laboratory, and Radiological Characteristics of Infected Patients With SARS-CoV-2 |
title_sort | covid-19 in pediatrics: demographic, clinical, laboratory, and radiological characteristics of infected patients with sars-cov-2 |
topic | Pediatrics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793734/ https://www.ncbi.nlm.nih.gov/pubmed/35096716 http://dx.doi.org/10.3389/fped.2021.808187 |
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