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COVID-19 in Pediatrics: Demographic, Clinical, Laboratory, and Radiological Characteristics of Infected Patients With SARS-CoV-2

The COVID-19 disease usually leads to mild infectious disease in children, but some develop serious complications. Here, we describe the characteristics of children with COVID-19 in northern Iran, the Golestan province. Ninety-one confirmed cases were enrolled in the study, aged 0–18 years. Demograp...

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Autores principales: Najafinejad, Maryam, Cheraghali, Fatemeh, Aghcheli, Bahman, Rajabi, Abdolhalim, Barati, Leila, Naziri, Hamed, Gharib, Mohammad Hadi, Tabarraei, Alijan, Nakstad, Britt, Tahamtan, Alireza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793734/
https://www.ncbi.nlm.nih.gov/pubmed/35096716
http://dx.doi.org/10.3389/fped.2021.808187
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author Najafinejad, Maryam
Cheraghali, Fatemeh
Aghcheli, Bahman
Rajabi, Abdolhalim
Barati, Leila
Naziri, Hamed
Gharib, Mohammad Hadi
Tabarraei, Alijan
Nakstad, Britt
Tahamtan, Alireza
author_facet Najafinejad, Maryam
Cheraghali, Fatemeh
Aghcheli, Bahman
Rajabi, Abdolhalim
Barati, Leila
Naziri, Hamed
Gharib, Mohammad Hadi
Tabarraei, Alijan
Nakstad, Britt
Tahamtan, Alireza
author_sort Najafinejad, Maryam
collection PubMed
description The COVID-19 disease usually leads to mild infectious disease in children, but some develop serious complications. Here, we describe the characteristics of children with COVID-19 in northern Iran, the Golestan province. Ninety-one confirmed cases were enrolled in the study, aged 0–18 years. Demographic, clinical, comorbidity, laboratory, and radiological data were compared based on the disease severity (admitted to intensive care unit (ICU) or not) and disease outcome (recovered or deceased). Sixteen (17.5%) cases were hospitalized in ICU, and 8/91 (8.8%) deceased. Fever and cough were the most common clinical symptoms. Among all symptoms notified there were no significant differences between severe and milder cases, or between those who deceased and recovered. Failure to thrive (FTT), malignant disease and neurological disease were significantly more prevalent in severe cases as was frequently reported comorbidities. Laterality, ground-glass opacity, and lung consolidation were the most common findings in chest computed tomography. The data confirms that the COVID-19 disease has various presentations in children, and clinical, laboratory, and radiological findings may help predict the development of severe forms of COVID-19 among children.
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spelling pubmed-87937342022-01-28 COVID-19 in Pediatrics: Demographic, Clinical, Laboratory, and Radiological Characteristics of Infected Patients With SARS-CoV-2 Najafinejad, Maryam Cheraghali, Fatemeh Aghcheli, Bahman Rajabi, Abdolhalim Barati, Leila Naziri, Hamed Gharib, Mohammad Hadi Tabarraei, Alijan Nakstad, Britt Tahamtan, Alireza Front Pediatr Pediatrics The COVID-19 disease usually leads to mild infectious disease in children, but some develop serious complications. Here, we describe the characteristics of children with COVID-19 in northern Iran, the Golestan province. Ninety-one confirmed cases were enrolled in the study, aged 0–18 years. Demographic, clinical, comorbidity, laboratory, and radiological data were compared based on the disease severity (admitted to intensive care unit (ICU) or not) and disease outcome (recovered or deceased). Sixteen (17.5%) cases were hospitalized in ICU, and 8/91 (8.8%) deceased. Fever and cough were the most common clinical symptoms. Among all symptoms notified there were no significant differences between severe and milder cases, or between those who deceased and recovered. Failure to thrive (FTT), malignant disease and neurological disease were significantly more prevalent in severe cases as was frequently reported comorbidities. Laterality, ground-glass opacity, and lung consolidation were the most common findings in chest computed tomography. The data confirms that the COVID-19 disease has various presentations in children, and clinical, laboratory, and radiological findings may help predict the development of severe forms of COVID-19 among children. Frontiers Media S.A. 2022-01-13 /pmc/articles/PMC8793734/ /pubmed/35096716 http://dx.doi.org/10.3389/fped.2021.808187 Text en Copyright © 2022 Najafinejad, Cheraghali, Aghcheli, Rajabi, Barati, Naziri, Gharib, Tabarraei, Nakstad and Tahamtan. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
Najafinejad, Maryam
Cheraghali, Fatemeh
Aghcheli, Bahman
Rajabi, Abdolhalim
Barati, Leila
Naziri, Hamed
Gharib, Mohammad Hadi
Tabarraei, Alijan
Nakstad, Britt
Tahamtan, Alireza
COVID-19 in Pediatrics: Demographic, Clinical, Laboratory, and Radiological Characteristics of Infected Patients With SARS-CoV-2
title COVID-19 in Pediatrics: Demographic, Clinical, Laboratory, and Radiological Characteristics of Infected Patients With SARS-CoV-2
title_full COVID-19 in Pediatrics: Demographic, Clinical, Laboratory, and Radiological Characteristics of Infected Patients With SARS-CoV-2
title_fullStr COVID-19 in Pediatrics: Demographic, Clinical, Laboratory, and Radiological Characteristics of Infected Patients With SARS-CoV-2
title_full_unstemmed COVID-19 in Pediatrics: Demographic, Clinical, Laboratory, and Radiological Characteristics of Infected Patients With SARS-CoV-2
title_short COVID-19 in Pediatrics: Demographic, Clinical, Laboratory, and Radiological Characteristics of Infected Patients With SARS-CoV-2
title_sort covid-19 in pediatrics: demographic, clinical, laboratory, and radiological characteristics of infected patients with sars-cov-2
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793734/
https://www.ncbi.nlm.nih.gov/pubmed/35096716
http://dx.doi.org/10.3389/fped.2021.808187
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