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Maternal High-Fat Diet Alters the Characteristics of Astrocytes and Worsens the Outcome of Stroke in Rat Offspring, Which Improves After FGF21 Administration

Background: Maternal high-fat diet (MHFD) has been shown to increase susceptibility to neurological disease in later offspring, but the underlying mechanism is not clear. Fibroblast growth factor 21 (FGF21) has been reported to have a neuroprotective effect in stroke, but its mechanism of action rem...

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Detalles Bibliográficos
Autores principales: Li, Yanxuan, Lin, Mengqi, Lin, Ping, Xia, Nengzhi, Li, Xiaokun, Lin, Li, Yang, Yunjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793739/
https://www.ncbi.nlm.nih.gov/pubmed/35096806
http://dx.doi.org/10.3389/fcell.2021.731698

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