The Role of Uptake and Efflux Transporters in the Disposition of Glucuronide and Sulfate Conjugates

Glucuronidation and sulfation are the most typical phase II metabolic reactions of drugs. The resulting glucuronide and sulfate conjugates are generally considered inactive and safe. They may, however, be the most prominent drug-related material in the circulation and excreta of humans. The glucuron...

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Detalles Bibliográficos
Autores principales: Järvinen, Erkka, Deng, Feng, Kiander, Wilma, Sinokki, Alli, Kidron, Heidi, Sjöstedt, Noora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793843/
https://www.ncbi.nlm.nih.gov/pubmed/35095509
http://dx.doi.org/10.3389/fphar.2021.802539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793843/
https://www.ncbi.nlm.nih.gov/pubmed/35095509
http://dx.doi.org/10.3389/fphar.2021.802539

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